| |
NAFLD (23,295)
|
Mild-NAFLD (18,260)
|
Moderate-NAFLD (4896)
|
Severe-NAFLD (139)
|
|---|
|
Parameter (n, %)
|
H.pylori− (14,678)
|
H.pylori+ (8617)
|
P value
|
H.pylori− (11,549)
|
H.pylori+ (6711)
|
P value
|
H.pylori− (3044)
|
H.pylori+ (1852)
|
P value
|
H.pylori− (85)
|
H.pylori+ (54)
|
P value
|
|---|
|
Liver function
| | | | | | | | | | | | |
|
AST increased
|
893 (6.2%)
|
529 (6.2%)
|
0.911
|
467 (4.1%)
|
261 (3.9%)
|
0.582
|
382 (12.7%)
|
217 (11.9%)
|
0.393
|
20 (24.7%)
|
11 (21.6%)
|
0.833
|
|
ALT increased
|
4492 (30.7%)
|
2572 (29.9%)
|
0.237
|
2796 (24.3%)
|
1456 (21.8%)
|
< 0.001
|
1643 (54.2%)
|
976 (52.9%)
|
0.391
|
53 (63.1%)
|
40 (75.5%)
|
0.139
|
|
GGT increased
|
3580 (24.8%)
|
2123 (25.0%)
|
0.776
|
2456 (21.6%)
|
1382 (20.9%)
|
0.242
|
1093 (36.5%)
|
677 (37.0%)
|
0.712
|
31 (38.3%)
|
17 (33.3%)
|
0.584
|
|
Renal function
| | | | | | | | | | | | |
|
Scr increased
|
53 (0.4%)
|
25 (0.3%)
|
0.411
|
39 (0.3%)
|
22 (0.3%)
|
0.995
|
14 (0.5%)
|
3 (0.2%)
|
0.130
|
0
|
0
|
-
|
|
BUN increased
|
824 (5.6%)
|
550 (6.4%)
|
0.014
|
670 (5.8%)
|
415 (6.2%)
|
0.299
|
149 (4.9%)
|
104 (5.6%)
|
0.287
|
5 (6.0%)
|
4 (7.4%)
|
0.737
|
|
Carbohydrate metabolism
| | | | | | | | | | | | |
|
FBG increased
|
1097 (8.5%)
|
810 (10.6%)
|
< 0.001
|
727 (7.1%)
|
532 (9.0%)
|
< 0.001
|
361 (13.4%)
|
262 (15.8%)
|
0.033
|
9 (11.1%)
|
4 (7.7)
|
0.568
|
|
HbA1C increased
|
1286 (10.7%)
|
930 (12.8%)
|
< 0.001
|
880 (9.3%)
|
611 (10.8%)
|
0.003
|
395 (16.0%)
|
311 (19.9%)
|
0.002
|
11 (18.3%)
|
8 (22.22%)
|
0.792
|
|
Lipid metabolism
| | | | | | | | | | | | |
|
Total cholesterol increased
|
1533 (10.5%)
|
918 (10.7%)
|
0.627
|
1149 (10.0%)
|
679 (10.1%)
|
0.721
|
375 (12.3%)
|
230 (12.4%)
|
0.929
|
9 (10.7%)
|
9 (16.7%)
|
0.315
|
|
LDL-C increased
|
1114 (7.6%)
|
706 (8.2%)
|
0.100
|
849 (7.4%)
|
540 (8.1%)
|
0.087
|
259 (8.5%)
|
163 (8.8%)
|
0.714
|
6 (7.1%)
|
3 (5.6%)
|
1.000
|
|
HDL-C decreased
|
2177 (14.7%)
|
1291 (15.0%)
|
0.746
|
1500 (13.0%)
|
873 (13.0%)
|
0.964
|
652 (21.4%)
|
398 (21.5%)
|
0.943
|
25 (29.8%)
|
20 (37.0%)
|
0.457
|
|
Triglycerides increased
|
4953 (33.8%)
|
3049 (35.4%)
|
0.012
|
3433 (29.8%)
|
2118 (31.6%)
|
0.010
|
1484 (48.8%)
|
902 (48.8%)
|
0.976
|
36 (42.9%)
|
29 (53.7%)
|
0.226
|
- H. pylori, Helicobacter pylori; BMI, body mass index; BP, blood pressure; FBG, fasting blood glucose; HbA1C, glycated hemoglobin; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase; Scr, serum creatinine; BUN, blood urea nitrogen; NAFLD, nonalcoholic fatty liver disease
