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Table 3 Baseline and end of study measurements compared between home-based exercise training and control groups

From: Effect of a 12-week home-based exercise training program on aerobic capacity, muscle mass, liver and spleen stiffness, and quality of life in cirrhotic patients: a randomized controlled clinical trial

Characteristics

HoBET group (n = 20)

Control group (n = 20)

Change in mean

(95% CI)

p-value between groups*

, 95%CI

Baseline

(mean ± SD)

End of study

(mean ± SD)

Within group

p

Baseline

(mean ± SD)

End of study

(mean ± SD)

Within group

p

Body mass index (kg/m2)

25.2 ± 2.7

25.2 ± 2.7

0.71

25.2 ± 3.4

25.0 ± 3.3

1.00

2.3 (−0.2, 0.6)

0.30

(−0.2–0.7)

% Fat

24.6 ± 7.0

25.1 ± 6.6

0.44

29.1 ± 9.1

28.3 ± 9.1

0.08

1.24 (−0.27, 2.74)

0.22

(−0.6–2.5)

Muscle mass (kg)

50.8 ± 7.6

50.6 ± 7.9

0.48

44.4 ± 7.5

44.5 ± 7.4

0.86

−0.31 (−1.24, 0.62)

0.53

(−0.7–1.3)

6MWT (meters)

479.8 ± 61.1

498.6 ± 77.8

0.08

470.6 ± 8.0

476.2 ± 91.2

0.08

13.3(−14.9–41.5)

0.36

(−15.5–41.7)

Transient elastography

Liver stiffness (kPa)

14.0 ± 9.6

12.2 ± 7.6

0.016

16.6 ± 9.2

14.0 ± 8.1

0.016

0.7 (−1.2, 2.7)

0.77

(−1.3–1.8)

Spleen stiffness (kPa)

25.8 ± 16.2

36.1 ± 43.6

0.30

33.7 ± 25.9

31.7 ± 22.4

0.30

12.3 (−8.7, 33.3)

0.37

(−11.6–30.4)

Thigh muscle mass

Thigh circumference (cm)

49.2 ± 3.4

49.5 ± 3.3

0.26

48.3 ± 4.7

48.2 ± 4.3

0.58

0.5 (−0.31, 1.31)

0.13

(−0.2–1.4)

Average feather index (cm/m2)

0.82 ± 0.16

0.89 ± 0.21

0.20

0.86 ± 0.26

0.85 ± 0.20

0.61

0.07 (−0.03, 0.16)

0.18

(−0.03–0.15)

Average compression index (cm/m2)

0.62 ± 0.12

0.70 ± 0.17

0.09

0.67 ± 0.17

0.63 ± 0.14

0.07

0.02 (0.02, 0.19)

0.03

(0.01–0.17)

Quality of life

Abdominal symptoms

5.9 ± 1.0

5.9 ± 1.3

0.95

5.3 ± 1.3

5.3 ± 1.4

1.0

0.01 (0.7, 0.7)

0.62 (−0.5–0.8)

Fatigue

5.1 ± 1.1

5.6 ± 0.9

0.009

4.7 ± 1.1

4.9 ± 1.1

0.02

0.3 (−0.1, 0.6)

0.05

(0.0–0.67)

Systemic symptoms

5.8 ± 0.8

6.0 ± 0.7

0.22

5.2 ± 1.2

4.7 ± 0.8

0.95

0.2 (−0.3, 0.6)

0.12

(−0.09–0.8)

Activity

5.8 ± 0.8

6.3 ± 0.9

0.01

5.3 ± 1.2

6.3 ± 1.0

0.13

0.3 (−0.3, 0.9)

0.08

(−0.06–0.97)

Emotional function

5.4 ± 1.0

5.8 ± 0.9

0.03

4.9 ± 1.3

5.8 ± 0.9

0.03

−0.05 (−0.5, 0.4)

0.68

(−0.3–0.5)

Worry

5.8 ± 1.5

5.9 ± 1.1

0.66

5.1 ± 1.4

5.4 ± 1.4

0.06

−0.13 (−0.7, 0.5)

0.72

(−0.4–0.6)

Average CLDQ

5.6 ± 0.9

5.9 ± 0.8

0.03

5.1 ± 1.1

5.3 ± 1.1

0.01

0.09 (−0.2, 0.4)

0.23

(−0.7–2.8)

  1. A p-value < 0.05 indicates statistical significance
  2. *p-value calculated by analysis of covariance (ANCOVA)
  3. 6MWT six-minute walk test, CLDQ chronic liver disease questionnaire, HoBET home-based exercise training