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Table 3 Baseline and end of study measurements compared between home-based exercise training and control groups

From: Effect of a 12-week home-based exercise training program on aerobic capacity, muscle mass, liver and spleen stiffness, and quality of life in cirrhotic patients: a randomized controlled clinical trial

Characteristics HoBET group (n = 20) Control group (n = 20) Change in mean
(95% CI)
p-value between groups*
, 95%CI
Baseline
(mean ± SD)
End of study
(mean ± SD)
Within group
p
Baseline
(mean ± SD)
End of study
(mean ± SD)
Within group
p
Body mass index (kg/m2) 25.2 ± 2.7 25.2 ± 2.7 0.71 25.2 ± 3.4 25.0 ± 3.3 1.00 2.3 (−0.2, 0.6) 0.30
(−0.2–0.7)
% Fat 24.6 ± 7.0 25.1 ± 6.6 0.44 29.1 ± 9.1 28.3 ± 9.1 0.08 1.24 (−0.27, 2.74) 0.22
(−0.6–2.5)
Muscle mass (kg) 50.8 ± 7.6 50.6 ± 7.9 0.48 44.4 ± 7.5 44.5 ± 7.4 0.86 −0.31 (−1.24, 0.62) 0.53
(−0.7–1.3)
6MWT (meters) 479.8 ± 61.1 498.6 ± 77.8 0.08 470.6 ± 8.0 476.2 ± 91.2 0.08 13.3(−14.9–41.5) 0.36
(−15.5–41.7)
Transient elastography
Liver stiffness (kPa) 14.0 ± 9.6 12.2 ± 7.6 0.016 16.6 ± 9.2 14.0 ± 8.1 0.016 0.7 (−1.2, 2.7) 0.77
(−1.3–1.8)
Spleen stiffness (kPa) 25.8 ± 16.2 36.1 ± 43.6 0.30 33.7 ± 25.9 31.7 ± 22.4 0.30 12.3 (−8.7, 33.3) 0.37
(−11.6–30.4)
Thigh muscle mass
Thigh circumference (cm) 49.2 ± 3.4 49.5 ± 3.3 0.26 48.3 ± 4.7 48.2 ± 4.3 0.58 0.5 (−0.31, 1.31) 0.13
(−0.2–1.4)
Average feather index (cm/m2) 0.82 ± 0.16 0.89 ± 0.21 0.20 0.86 ± 0.26 0.85 ± 0.20 0.61 0.07 (−0.03, 0.16) 0.18
(−0.03–0.15)
Average compression index (cm/m2) 0.62 ± 0.12 0.70 ± 0.17 0.09 0.67 ± 0.17 0.63 ± 0.14 0.07 0.02 (0.02, 0.19) 0.03
(0.01–0.17)
Quality of life
Abdominal symptoms 5.9 ± 1.0 5.9 ± 1.3 0.95 5.3 ± 1.3 5.3 ± 1.4 1.0 0.01 (0.7, 0.7) 0.62 (−0.5–0.8)
Fatigue 5.1 ± 1.1 5.6 ± 0.9 0.009 4.7 ± 1.1 4.9 ± 1.1 0.02 0.3 (−0.1, 0.6) 0.05
(0.0–0.67)
Systemic symptoms 5.8 ± 0.8 6.0 ± 0.7 0.22 5.2 ± 1.2 4.7 ± 0.8 0.95 0.2 (−0.3, 0.6) 0.12
(−0.09–0.8)
Activity 5.8 ± 0.8 6.3 ± 0.9 0.01 5.3 ± 1.2 6.3 ± 1.0 0.13 0.3 (−0.3, 0.9) 0.08
(−0.06–0.97)
Emotional function 5.4 ± 1.0 5.8 ± 0.9 0.03 4.9 ± 1.3 5.8 ± 0.9 0.03 −0.05 (−0.5, 0.4) 0.68
(−0.3–0.5)
Worry 5.8 ± 1.5 5.9 ± 1.1 0.66 5.1 ± 1.4 5.4 ± 1.4 0.06 −0.13 (−0.7, 0.5) 0.72
(−0.4–0.6)
Average CLDQ 5.6 ± 0.9 5.9 ± 0.8 0.03 5.1 ± 1.1 5.3 ± 1.1 0.01 0.09 (−0.2, 0.4) 0.23
(−0.7–2.8)
  1. A p-value < 0.05 indicates statistical significance
  2. *p-value calculated by analysis of covariance (ANCOVA)
  3. 6MWT six-minute walk test, CLDQ chronic liver disease questionnaire, HoBET home-based exercise training