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Table 2 The differences of GD together with AIH

From: Graves’ disease overlapping with chronic hepatitis B and methimazole-induced liver injury and autoimmune hepatitis: a case report

Year Authors Clinical features Diagnosis Therapy Effect Ref. no
1999 Inoue K, et al A 48-year F suffered from GD and AIH concurrently. A11 and DR4 are positive in HLA GD-associated AIH MMI fT4 and ALT were decreased simultaneously after MMI use [19]
2011 Sato et al A 58-year F had three-year GD, and then PTU-induced AI-DILI GD and PTU- induced AI-DILI PSL Elevated AST level decreased immediately by PSL [22]
2019 Sano et al A 15-year F suffered from GD and treated with MMI. She was ill with MMI-induced DILI with AIH futures GD and MMI- induced-DILI with AIH futures RIA, PSL Elevated aminotransferases couldn’t be controlled after RIA but normalized after one-month PSL [11]
2019 Sano et al A 21-year F suffered from GD complicated with classical type II AIH GD and type II AIH RIA, PSL, LT AIH couldn’t be controlled by RIA and PSL, and received LT [11]
2019 Sano et al A 39-year-F suffered from GD complicated with classical AIH GD and AIH PSL, RIA, LT AIH couldn’t be controlled by PSL and RIA, and received LT [11]
2019 Sawhney et al A 24-year F was ill with classical type I AIH, and then GD was found Type I AIH and GD PSL, AZA, RIA AIH be effectively controlled by the combination of PSL and AZA and RIA [20]
  1. F female, GD graves’ disease, AIH autoimmune hepatitis, AI-DILI autoimmune-like drug-induced liver injury, MMI methimazole, PTU propylthiouracil, PSL prednisone, RIA radioactive iodine ablation, LT liver transplant, AZA azathioprine