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Table 2 Univariate analysis of prognostic factors in patients with rectal adenocarcinoma undergoing surgery

From: Nomogram to predict cause-specific mortality of patients with rectal adenocarcinoma undergoing surgery: a competing risk analysis

Variables

Classification

Cause-specific death (%)

Death due to other causes (%)

1-year (95% CI)

3-year (95% CI)

5-year (95% CI)

P value

1-year (95% CI)

3-year (95% CI)

5-year (95% CI)

P value

Age

    

< 0.001

   

< 0.001

 

< 65

2.39 (2.34–2.45)

12.21 (11.95–12.48)

21.55 (21.08–22.02)

 

0.67 (0.65–0.68)

2.04 (1.99–2.09)

3.39 (3.30–3.47)

 
 

≥ 65

7.39 (7.17–7.60)

19.41 (18.88–19.94)

27.43 (26.70–28.16)

 

3.70 (3.58–3.81)

9.04 (8.76–9.31)

14.39 (13.93–14.85)

 

Race

    

< 0.001

   

0.0027

 

White

4.44 (4.37–4.50)

14.92 (14.70–15.14)

23.34 (23.00–23.69)

 

1.99 (1.96–2.02)

5.04 (4.96–5.12)

8.14 (8.00–8.29)

 
 

Black

5.23 (4.39–6.06)

19.36 (16.48–22.25)

30.72 (26.31–35.12)

 

1.99 (1.66–2.31)

5.53 (4.60–6.47)

8.38 (6.85–9.90)

 
 

Other

3.86 (3.41–4.31)

14.10 (12.49–15.71)

23.89 (21.16–26.63)

 

1.22 (1.07–1.36)

3.63 (3.17–4.09)

6.58 (5.67–7.50)

 

Sex

    

0.1107

   

0.1401

 

Male

4.42 (4.32–4.51)

15.05 (14.75–15.35)

24.28 (23.79–24.76)

 

1.96 (1.91–2.00)

4.90 (4.79–5.01)

8.19 (7.99–8.38)

 
 

Female

4.46 (4.32–4.60)

15.36 (14.90–15.83)

23.51 (22.80–24.22)

 

1.83 (1.77–1.89)

4.97 (4.80–5.13)

7.70 (7.43–7.98)

 

MS

    

< 0.001

   

< 0.001

 

Married

3.40 (3.34–3.47)

12.76 (12.51–13.02)

20.87 (20.45–21.29)

 

1.50 (1.47–1.53)

3.80 (3.72–3.88)

6.51 (6.36–6.67)

 
 

Unmarried

6.08 (5.89–6.28)

19.06 (18.49–19.63)

29.00 (28.15–29.85)

 

2.56 (2.47–2.64)

6.74 (6.51–6.97)

10.40 (10.02–10.78)

 

AJCC

    

< 0.001

   

< 0.001

 

I

1.76 (1.64–1.87)

4.23 (3.94–4.51)

7.93 (7.36–8.49)

 

2.00 (1.87–2.13)

5.52 (5.16–5.89)

9.77 (9.09–10.45)

 
 

II

2.67 (2.55–2.79)

9.52 (9.09–9.95)

16.42 (15.66–17.19)

 

1.99 (1.90–2.08)

5.28 (5.04–5.53)

9.30 (8.83–9.76)

 
 

III

4.21 (4.08–4.34)

15.74 (15.29–16.20)

26.14 (25.38–26.89)

 

1.77 (1.71–1.82)

4.56 (4.42–4.71)

6.80 (6.56–7.04)

 
 

IV

15.82 (14.06–17.58)

51.47 (47.83–55.11)

70.71 (67.22–74.19)

 

2.05 (1.78–2.31)

4.21 (3.65–4.77)

5.38 (4.62–6.14)

 

TS

    

< 0.001

   

0.0007

 

< 4 cm

2.93 (2.85–3.02)

11.48 (11.15–11.80)

19.47 (18.91–20.02)

 

1.72 (1.67–1.77)

4.46 (4.33–4.60)

7.28 (7.04–7.51)

 
 

4–8 cm

5.15 (5.01–5.28)

17.41 (16.98–17.84)

26.74 (26.09–27.39)

 

2.16 (2.10–2.22)

5.44 (5.29–5.59)

8.74 (8.48–9.01)

 
 

≥ 8 cm

8.40 (7.16–9.64)

22.38 (19.31–25.46)

32.87 (28.38–37.37)

 

1.41 (1.18–1.63)

4.44 (3.68–5.19)

7.61 (6.18–9.04)

 

LN

    

< 0.001

   

< 0.001

 

0

2.59 (2.54–2.65)

8.65 (8.47–8.84)

14.74 (14.41–15.06)

 

1.83 (1.79–1.87)

4.95 (4.84–5.05)

8.73 (8.52–8.94)

 
 

1–3

5.19 (4.91–5.46)

19.25 (18.30–20.19)

31.39 (29.92–32.85)

 

1.98 (1.87–2.09)

4.76 (4.49–5.03)

6.93 (6.51–7.35)

 
 

4–8

9.33 (8.27–10.39)

30.34 (27.51–33.17)

44.68 (41.06–48.30)

 

2.28 (2.00–2.56)

5.59 (4.90–6.28)

7.40 (6.45–8.35)

 
 

> 8

15.10 (11.19–19.01)

48.35 (40.20–56.51)

62.11 (53.82–70.40)

 

1.75 (1.22–2.27)

3.93 (2.74–5.12)

4.99 (3.41–6.57)

 

Radiation

    

< 0.001

   

< 0.001

 

None

7.95 (7.66–8.24)

20.13 (19.45–20.80)

27.27 (26.37–28.16)

 

3.47 (3.34–3.61)

8.20 (7.89–8.51)

12.51 (12.02–13.01)

 
 

Yes

2.70 (2.65–2.76)

12.71 (12.47–12.95)

22.36 (21.94–22.79)

 

1.14 (1.11–1.16)

3.29 (3.23–3.36)

5.69 (5.56–5.82)

 

Chemotherapy

    

< 0.001

   

< 0.001

 

None

7.91 (7.56–8.26)

16.34 (15.66–17.03)

22.00 (21.08–22.91)

 

3.91 (3.73–4.09)

9.25 (8.83–9.67)

14.26 (13.59–14.92)

 
 

Yes

3.13 (3.08–3.19)

14.76 (14.51–15.01)

24.84 (24.42–25.26)

 

1.15 (1.13–1.17)

3.27 (3.21–3.33)

5.53 (5.41–5.64)

 
  1. MS, marital status; TS, tumor size; LN, number of metastasis lymph nodes