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Table 2 Risk factors of CR-POPF: Univariate and multivariate logistic regression analysis

From: Vater’s ampullary carcinoma increases the risk of clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy: A retrospective and propensity score-matched analysis

Variables Univariate analysis Multivariate analysis
  OR (95%CI) P value OR (95%CI) P value
Age 1.031 (1.003–1.060) 0.030 NA NA
Sex, male vs. female 0.677 (0.348–1.317) 0.251   
BMI 1.041 (0.948–1.142) 0.399   
Diabetic mellitus 1.122 (0.531–2.372) 0.763   
Hypertension 1.031 (0.545–1.950) 0.926   
History of surgery 0.523 (0.271–1.012) 0.054 NA NA
Smoking 0.455 (0.180–1.153) 0.097 NA NA
Alcohol 0.835 (0.310–2.248) 0.721   
Preoperative jaundice, yes vs. no 1.949 (0.725–5.242) 0.186   
Preoperative biliary drainage, yes vs. no 0.961 (0.371–2.489) 0.934   
ALT 0.999 (0.992–1.007) 0.862   
AST 0.998 (0.989–1.008) 0.719   
AKP 0.998 (0.996–1.001) 0.136   
γ-GGT 1.000 (0.999–1.002) 0.473   
TB 0.983 (0.951–1.017) 0.321   
DB 1.024 (0.979–1.072) 0296   
Albumin 1.101 (0.971–1.249) 0.134   
WBC 1.157 (0.969–1.382) 0.107   
Hemoglobin 1.014 (0.992–1.036) 0.217   
Platelet 1.002 (0.998–1.006) 0.425   
Pathology, VAC vs. non-VAC 2.423 (1.223–4.800) 0.011 1.824 (1.087–3.060) 0.023
Surgical method, PD vs. PPPD 0.496 (0.253–0.973) 0.041 NA NA
Vessel resection, yes vs. no 1.051 (0.186–5.940) 0.955   
Operating time 1.003 (0.999–1.006) 0.153   
Blood loss volume 0.999 (0.998–1.000) 0.207   
Blood transfusion 1.000 (1.000–1.001) 0.311   
  1. BMI: body mass index; ALT: alanine aminotransferase, AST: aspartate aminotransferase, AKP: alkaline phosphate, γ-GGT:γ-glutamyl transferase, TB: total bilirubin, DB: direct bilirubin, WBC: white blood cell, NA: not applicable, VAC: Vater’s ampullary carcinoma; PD: pancreaticoduodenectomy; PPPD: pylorus-preserving pancreaticoduodenectomy; CR-POPF: Clinically relevant postoperative pancreatic fistula (Grade B/ C); CI: confidence interval; OR: odds ratio