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Table 2 Risk factors of CR-POPF: Univariate and multivariate logistic regression analysis

From: Vater’s ampullary carcinoma increases the risk of clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy: A retrospective and propensity score-matched analysis

Variables

Univariate analysis

Multivariate analysis

 

OR (95%CI)

P value

OR (95%CI)

P value

Age

1.031 (1.003–1.060)

0.030

NA

NA

Sex, male vs. female

0.677 (0.348–1.317)

0.251

  

BMI

1.041 (0.948–1.142)

0.399

  

Diabetic mellitus

1.122 (0.531–2.372)

0.763

  

Hypertension

1.031 (0.545–1.950)

0.926

  

History of surgery

0.523 (0.271–1.012)

0.054

NA

NA

Smoking

0.455 (0.180–1.153)

0.097

NA

NA

Alcohol

0.835 (0.310–2.248)

0.721

  

Preoperative jaundice, yes vs. no

1.949 (0.725–5.242)

0.186

  

Preoperative biliary drainage, yes vs. no

0.961 (0.371–2.489)

0.934

  

ALT

0.999 (0.992–1.007)

0.862

  

AST

0.998 (0.989–1.008)

0.719

  

AKP

0.998 (0.996–1.001)

0.136

  

γ-GGT

1.000 (0.999–1.002)

0.473

  

TB

0.983 (0.951–1.017)

0.321

  

DB

1.024 (0.979–1.072)

0296

  

Albumin

1.101 (0.971–1.249)

0.134

  

WBC

1.157 (0.969–1.382)

0.107

  

Hemoglobin

1.014 (0.992–1.036)

0.217

  

Platelet

1.002 (0.998–1.006)

0.425

  

Pathology, VAC vs. non-VAC

2.423 (1.223–4.800)

0.011

1.824 (1.087–3.060)

0.023

Surgical method, PD vs. PPPD

0.496 (0.253–0.973)

0.041

NA

NA

Vessel resection, yes vs. no

1.051 (0.186–5.940)

0.955

  

Operating time

1.003 (0.999–1.006)

0.153

  

Blood loss volume

0.999 (0.998–1.000)

0.207

  

Blood transfusion

1.000 (1.000–1.001)

0.311

  
  1. BMI: body mass index; ALT: alanine aminotransferase, AST: aspartate aminotransferase, AKP: alkaline phosphate, γ-GGT:γ-glutamyl transferase, TB: total bilirubin, DB: direct bilirubin, WBC: white blood cell, NA: not applicable, VAC: Vater’s ampullary carcinoma; PD: pancreaticoduodenectomy; PPPD: pylorus-preserving pancreaticoduodenectomy; CR-POPF: Clinically relevant postoperative pancreatic fistula (Grade B/ C); CI: confidence interval; OR: odds ratio