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Table 1 Clinical characteristic of all patients

From: Vater’s ampullary carcinoma increases the risk of clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy: A retrospective and propensity score-matched analysis

Characteristic

Total(n = 263)

Age (mean ± SD), years

61.5 ± 12.1

Sex, n (%)

 

 Male

163 (62.0)

 Female

100 (38.0)

BMI (mean ± SD), kg/m2

23.5 ± 3.3

Diabetic mellitus, n (%)

47 (17.9)

Hypertension, n (%)

89 (33.8)

History of surgery, n (%)

79 (30.0)

Smoking, n (%)

61 (23.2)

Alcohol, n (%)

77 (29.3)

Preoperative jaundice, n (%)

103 (39.2)

Preoperative biliary drainage, n (%)

77 (29.3)

ALT (median, IQR), U/L

45.5 (17.8–102.8)

AST (median, IQR), U/L

30.3 (17.9–63.5)

AKP (median, IQR), U/L

141.2 (69.5–290.2)

γ-GGT (median, IQR), U/L

130.6 (22.9–387.8)

TB (median, IQR), μmol/L

16.0 (9.2–58.6)

DB (median, IQR), μmol/L

6.5 (2.3–45.2)

Albumin (mean ± SD), g/L

38.8 ± 3.1

WBC(mean ± SD), × 109/L

5.8 ± 1.8

Hemoglobin (mean ± SD), g/L

122.8 ± 17.9

Platelet(mean ± SD), × 109/L

230.9 ± 86.8

Pathology diagnosis, n (%)

 

 VAC

94 (35.7)

 PDAC

61 (23.2)

 DCC

24 (9.1%)

 IPMN

25 (9.5%)

 SCN

10 (3.8%)

 pNET

9 (3.4%)

 SPN

6 (2.3%)

 MCN

4 (1.5%)

 CP

4 (1.5%)

 Others

26 (9.9%)

Surgical method, n (%)

 

 PD

186 (70.7)

 PPPD

77 (29.3)

Vessel resection, n (%)

 

 Yes

9 (3.4)

 No

254 (96.6)

Pancreatic texture

 

 Firm

36 (13.7)

 Soft

227 (86.3)

Diameter of the MPD (mm)

3.0 (2.0–5.0)

Fistula risk score

6.0 (4.0–7.0)

Operating time (mean ± SD), min

379.4 ± 96.9

Blood loss volume (median, IQR), ml

400.0 (300.0–700.0)

Blood transfusion (median, IQR), ml

0.0 (0.0–700.0)

CR-POPF, n (%)

99 (37.6)

Biliary leakage, n (%)

16 (6.1)

DGE, n (%)

94 (35.7)

PPH, n (%)

22 (8.4)

Chylous fistula, n (%)

31 (11.8)

Major postoperative complications, n (%)

57 (21.7)

Wound infection, n (%)

14 (5.3)

Intra-abdominal infection, n (%)

106 (40.3)

Bacteremia, n (%)

14 (5.3)

Pneumonia, n (%)

8 (3.0)

Urinary tract infection, n (%)

3 (1.4)

  1. SD: standard deviation; IQR: interquartile; BMI: body mass index; ALT: alanine aminotransferase, AST: aspartate aminotransferase, AKP: alkaline phosphate, γ-GGT:γ-glutamyl transferase, TB:total bilirubin, DB: direct bilirubin; WBC: white blood cell; VAC: Vater’s ampullary carcinoma; PDAC: pancreatic ductal adenocarcinoma; DCC: distal cholangiocarcinoma; IPMN: intraductal papillary mucinous neoplasm; SPN: solid pseudopapillary neoplasm of the pancreas; SCN: pancreatic serous cystadenoma; MCN: mucinous cystadenoma of pancreas; pNET: pancreatic neuroendocrine tumor; CP: chronic pancreatitis; MPD: main pancreatic duct; PD: pancreaticoduodenectomy; PPPD: pylorus-preserving pancreaticoduodenectomy; CR-POPF: Clinically relevant postoperative pancreatic fistula (Grade B/ C), PPH: post-pancreatectomy hemorrhage; DGE: delayed gastric emptying