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Table 2 Baseline characteristics of ACLF patients

From: Association between plasma level of superoxide dismutase and survival of patients with acute-on-chronic liver failure

Variables n = 124 Non-survivors
n = 61
Survivors
n = 63
P value
Age (yr) 47.52 ± 11.88 49.21 ± 1.37 45.89 ± 1.62 0.121
Sex(M/F) 103/21 51/10 52/11 0.874
ACLF etiology     
Acute hepatic insult, n (%)     
Alcoholic hepatitis 16 (12.90%) 8 (13.11%) 8 (12.70%) 0.888
HBV reactivation 65 (52.42%) 34 (55.74%) 31 (49.21%) 0.467
Bacterial infection 34 (27.42%) 17(27.87%) 17 (26.98%) 0.912
Others 9 (7.26%) 2 (3.28%) 7 (11.11%) 0.093
Underlying CLD, n (%)     
CHB 87 (70.16%) 45 (73.77%) 43 (68.25%) 0.499
ALD 21 (16.94%) 8 (13.11%) 13 (20.63%) 0.264
NAFLD 16 (12.90%) 8 (13.11%) 7 (11.11%) 0.732
Clinic events at presentation, n (%)     
Ascites 124 (100%) 61 (100%) 63 (100%)  
Jaundice 124 (100%) 61 (100%) 63 (100%)  
AKI 30 (24.19%) 20 (32.79%) 9 (14.29%) 0.015
HE 43 (34.68%) 31 (50.82%) 12 (19.05%)  < 0.01
Acute variceal bleed 17 (13.71%) 9 (14.75%) 8 (12.70%) 0.739
SBP 9 (7.3%) 4 (6.56%) 5 (7.94%) 0.767
Parameter     
PT (%) 37.76 ± 14.54 36.69 ± 221 38.81 ± 1.44 0.421
Fb (g/L) 1.56 ± 0.71 1.59 ± 0.11 1.54 ± 0.07 0.678
INR 2.09 ± 0.69 2.37 ± 0.11 1.82 ± 0.05  < 0.01
WBC(1 × 109/L) 14.46 ± 8.47 7.60 ± 0.57 6.11 ± 0.35 0.027
PLT (1 × 109/L) 99.90 ± 61.41 89.85 ± 6.44 109.6 ± 8.82 0.074
ALT (U/L) 288.69 ± 396.73 230.5 ± 44.43 345.1 ± 55.16 0.109
GLU (mM) 5.83 ± 3.32 6.15 ± 0.49 5.54 ± 0.36 0.316
TBIL (μM) 320.62 ± 136.81 404.1 ± 16.06 239.8 ± 11.77  < 0.01
CHOL (mM) 2.58 ± 0.90 2.52 ± 0.11 2.65 ± 0.12 0.420
CREA (μM) 66.09 ± 22.22 67.06 ± 2.89 65.17 ± 2.80 0.639
Organ failure     
Kidney, n (%) 11 (8.87%) 6 (9.84%) 5 (7.94%) 0.710
Cerebral, n (%) 20 (16.13%) 15 (24.59%) 5 (7.94%) 0.012
Coagulation, n (%) 43 (34.68%) 33 (52.46%) 10 (15.87%)  < 0.01
Circulation, n (%) 15 (12.09%) 8 (13.11%) 7 (11.11%) 0.732
Lung, n (%) 34 (27.42%) 22 (36.07%) 12 (19.05%) 0.034
Prognostic score     
MELD 25.16 ± 4.33 27.57 ± 0.51 22.83 ± 0.42  < 0.01