Variables | Healthy control (n = 30) | Cirrhosis (n = 30) | ALF (n = 30) | ACLF (n = 124) |
---|---|---|---|---|
Age (yr) | 42.54 ± 8.65 | 45.68 ± 5.39 | 45.23 ± 9.32 | 47.52 ± 11.88 |
Sex(M/F) | 24/6 | 24/6 | 24/6 | 103/21 |
PT (%) | 84.58 ± 15.77 | 76.36 ± 16.87 | 45.12 ± 11.27 | 37.76 ± 14.54*# |
Fb (g/L) | 2.68 ± 0.67 | 2.23 ± 0.95 | 1.65 ± 0.51 | 1.56 ± 0.71*# |
INR | 1.21 ± 0.19 | 1.37 ± 0.21 | 2.12 ± 0.34 | 2.09 ± 0.69*# |
WBC(1 × 109/L) | 5.68 ± 1.54 | 4.85 ± 1.75 | 15.56 ± 6.45 | 14.46 ± 8.47*# |
PLT (1 × 109/L) | 225.97 ± 38.54 | 115.04 ± 58.21 | 130.21 ± 21.35 | 99.90 ± 61.41*# |
ALT (U/L) | 25.21 ± 12.31 | 25.81 ± 12.32 | 355.75 ± 301.25 | 288.69 ± 396.73*# |
GLU (mM) | 4.39 ± 0.68 | 4.54 ± 0.98 | 5.23 ± 2.56 | 5.83 ± 3.32*# |
TBIL (μM) | 13.22 ± 3.79 | 19.88 ± 7.98 | 299.32 ± 178.23 | 320.62 ± 136.81*# |
CHOL (mM) | 3.97 ± 0.69 | 3.45 ± 0.91 | 2.78 ± 0.56 | 2.58 ± 0.90*# |
CREA (μM) | 49.67 ± 11.21 | 57.61 ± 9.81 | 65.23 ± 16.56 | 66.09 ± 22.22*# |
MELD | 25.05 ± 4.89 | 25.16 ± 4.33 |