Table 3 Crude and adjusted odds ratios and 95% confidence intervals for associations between clinical outcomes and CAR according to duration of UC. Short duration (≤ 7 years) (n = 143)
Variable | Prevalence (%) | Crude OR (95%CI) | Adjusted OR (95%CI) |
|---|---|---|---|
Short duration (≤ 7 years) (n = 143) | |||
Clinical remission | |||
Low CAR | 29/53 (54.7) | 1.00 | 1.00 |
Moderate CAR | 23/43 (53.5) | 0.95 (0.42–2.14) | 0.93 (0.38–2.27) |
High CAR | 20/47 (42.6) | 0.61 (0.28–1.35) | 0.61 (0.24–1.53) |
p for trend | 0.30 | ||
Mucosal healing (MES < 1) | |||
Low CAR | 12/43 (22.6) | 1.00 | 1.00 |
Moderate CAR | 12/43 (27.9) | 1.32 (0.52–3.37) | 1.51 (0.56–4.09) |
High CAR | 6/47 (12.8) | 0.50 (0.16–1.42) | 0.54 (0.16–1.74) |
p for trend | 0.39 | ||
Moderate to severe activity (MES 2 or 3) | |||
Low CAR | 17/53 (32.1) | 1.00 | 1.00 |
Moderate CAR | 17/43 (39.5) | 1.39 (0.60–3.23) | 1.36 (0.53–3.48) |
High CAR | 25/47 (53.2) | 2.41 (1.08–5.51) | 1.56 (0.62–3.95) |
p for trend | 0.35 | ||
Long duration (> 7 years) (n = 130) | |||
Clinical remission | |||
Low CAR | 29/40 (72.5) | 1.00 | 1.00 |
Moderate CAR | 33/46 (71.7) | 0.96 (0.37–2.48) | 1.38 (0.49–3.99) |
High CAR | 24/44 (54.6) | 0.46 (0.18–1.12) | 0.56 (0.20–1.56) |
p for trend | 0.24 | ||
Mucosal healing (MES < 1) | |||
Low CAR | 15/40 (37.5) | 1.00 | 1.00 |
Moderate CAR | 17/46 (37.0) | 0.98 (0.41–2.36) | 1.23 (0.47–3.25) |
High CAR | 9/44 (20.5) | 0.43 (0.16–1.12) | 0.44 (0.14–1.29) |
p for trend | 0.15 | ||
Moderate to severe activity (MES 2 or 3) | |||
Low CAR | 10/40 (25.0) | 1.00 | 1.00 |
Moderate CAR | 12/46 (26.1) | 1.06 (0.40–2.85) | 0.81 (0.27–2.36) |
High CAR | 20/44 (45.5) | 2.50 (1.004–6.53) | 2.95 (1.06–8.79) |
p for trend | 0.032 |