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Table 5 The diagnostic efficacy of FibroScan (LSM) for liver inflammation or fibrosis when PA ≥ 10

From: Diagnostic efficacy of FibroScan for liver inflammation in patients with chronic hepatitis B: a single-center study with 1185 liver biopsies as controls

LSM Group Cutoff (positive) Sensitivity (%) Specificity (%) Youden index AUC SE Z P (AUC = 0.5)
kPa ((PA ≥ 10))) G = 4 G = 1,2,3 > 11 87.43 66.21 0.536 0.832 0.016 20.809 < 0.0001
  G = 1,2 G = 3,4 ≤ 9.8 75.59 75.17 0.508 0.818 0.013 23.905 < 0.0001
  G = 1 G = 2,3,4  ≤ 8.6 78.33 68.70 0.470 0.775 0.024 11.542 < 0.0001
  S = 0,1,2 S = 3,4 ≤ 10.4 77.45 73.88 0.513 0.826 0.013 24.667 < 0.0001
  S = 0 S = 1,2,3,4 ≤ 8.6 83.33 67.69 0.510 0.791 0.029 10.126 < 0.0001
  S = 4 S = 0,1,2,3 > 11 83.05 65.37 0.484 0.807 0.017 17.740 < 0.0001
  S = 0,1 S = 2,3,4 ≤ 8.8 74.19 71.43 0.456 0.789 0.016 17.602 < 0.0001
  1. PA of liver tissue ≥ 10: There were significant differences in the LSMs among the liver inflammation or fibrosis grades (P < 0.0001)