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Table 5 The diagnostic efficacy of FibroScan (LSM) for liver inflammation or fibrosis when PA ≥ 10

From: Diagnostic efficacy of FibroScan for liver inflammation in patients with chronic hepatitis B: a single-center study with 1185 liver biopsies as controls

LSM

Group

Cutoff (positive)

Sensitivity (%)

Specificity (%)

Youden index

AUC

SE

Z

P (AUC = 0.5)

kPa ((PA ≥ 10)))

G = 4 G = 1,2,3

> 11

87.43

66.21

0.536

0.832

0.016

20.809

< 0.0001

 

G = 1,2 G = 3,4

≤ 9.8

75.59

75.17

0.508

0.818

0.013

23.905

< 0.0001

 

G = 1 G = 2,3,4

 ≤ 8.6

78.33

68.70

0.470

0.775

0.024

11.542

< 0.0001

 

S = 0,1,2 S = 3,4

≤ 10.4

77.45

73.88

0.513

0.826

0.013

24.667

< 0.0001

 

S = 0 S = 1,2,3,4

≤ 8.6

83.33

67.69

0.510

0.791

0.029

10.126

< 0.0001

 

S = 4 S = 0,1,2,3

> 11

83.05

65.37

0.484

0.807

0.017

17.740

< 0.0001

 

S = 0,1 S = 2,3,4

≤ 8.8

74.19

71.43

0.456

0.789

0.016

17.602

< 0.0001

  1. PA of liver tissue ≥ 10: There were significant differences in the LSMs among the liver inflammation or fibrosis grades (P < 0.0001)