Fig. 1
From: Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis
Intestinal Cldn7 knockout mice showed increased susceptibility to DSS-induced colitis. A Changes in the body weights of each mouse were measured as percent of the initial weight at the start of the experiments (CreERT2 + DSS vs. CreW + DSS, ****P < 0.0001, n = 6). B The DAI score was recorded daily (CreERT2 + DSS vs. CreW + DSS, **P < 0.01, ****P < 0.0001, n = 6). C, D Gross morphology and measurements of colon length (***P < 0.001, n = 6). E, F Representative H&E-stained colon sections in each group and colonic pathological scores for inflammation, extent of injury, crypt damage and regeneration (**P < 0.01, ***P < 0.001, n = 5)