Skip to main content

Table 4 Univariate and multivariate analysis of factors associated with advanced liver fibrosis

From: Serum ferritin levels are associated with advanced liver fibrosis in treatment-naive autoimmune hepatitis

Variables Univariate analysis Multivariate analysis
OR (95% CI) P OR (95% CI) P
Age (years) 1.053 (1.010, 1.097) 0.016   
Female 0.960 (0.312, 2.955) 0.943   
Autoantibodies positive 2.674 (0.694, 10.302) 0.153   
IgG (g/L) 1.084 (1.018, 1.154) 0.012 1.123 (1.023, 1.232) 0.014
ALT (U/L) 1.000 (0.999, 1.001) 0.820   
AST (U/L) 1.001 (0.999, 1.002) 0.314   
ALP (U/L) 1.006 (0.999, 1.014) 0.104   
GGT (U/L) 1.002 (0.999, 1.004) 0.273   
TBIL (μmol/L) 1.006 (1.001, 1.012) 0.029   
ALB (g/L) 0.921 (0.851, 0.996) 0.039   
PLT (× 109/L) 0.984 (0.976, 0.992)  < 0.001 0.988 (0.979, 0.997) 0.013
PT (s) 1.876 (1.317, 2.673)  < 0.001 1.758 (1.143, 2.704) 0.010
Iron (μmol/L) 1.023 (0.994, 1.054) 0.125   
Transferrin (g/L) 0.494 (0.250, 0.977) 0.043   
Ferritin (μg/L) 1.002 (1.001, 1.003) 0.002 1.002 (1.001, 1.004) 0.012
UIBC (μmol/L) 0.969 (0.947, 0.992) 0.008   
TIBC (μmol/L) 0.943 (0.905, 0.984) 0.006   
TSI (%) 1.023 (1.005, 1.041) 0.011   
  1. OR odds ratio, CI confidence interval, IgG immunoglobulin G, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, TBIL total bilirubin, ALB albumin, PLT platelet, PT prothrombin time, UIBC unsaturated iron binding capacity, TIBC total iron binding capacity, TSI transferrin saturation index