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Table 3 Correlations between iron metabolism related variables and clinical characteristics of patients

From: Serum ferritin levels are associated with advanced liver fibrosis in treatment-naive autoimmune hepatitis

Variables statistics

Iron (μmol/L)

Transferrin (g/L)

Ferritin (μg/L)

UIBC (μmol/L)

TIBC (μmol/L)

TSI (%)

r

P

r

P

r

P

r

P

r

P

r

P

Age (years)

0.296

0.003

 − 0.416

 < 0.001

0.349

 < 0.001

 − 0.394

 < 0.001

 − 0.375

 < 0.001

0.376

 < 0.001

IgG (g/L)

0.080

0.438

0.062

0.544

0.043

0.675

 − 0.057

0.577

0.003

0.978

0.083

0.420

ALT (U/L)

0.348

 < 0.001

 − 0.031

0.765

0.418

 < 0.001

 − 0.311

0.002

 − 0.091

0.375

0.332

0.001

AST (U/L)

0.462

 < 0.001

 − 0.097

0.346

0.460

 < 0.001

 − 0.415

 < 0.001

 − 0.107

0.299

0.453

 < 0.001

ALP (U/L)

0.310

0.002

 − 0.029

0.776

0.209

0.040

 − 0.251

0.013

 − 0.080

0.437

0.299

0.003

GGT (U/L)

0.408

 < 0.001

 − 0.104

0.312

0.340

0.001

 − 0.350

 < 0.001

 − 0.136

0.186

0.390

 < 0.001

TBIL (μmol/L)

0.498

 < 0.001

 − 0.220

0.030

0.395

 < 0.001

 − 0.526

 < 0.001

 − 0.249

0.014

0.533

 < 0.001

ALB (g/L)

 − 0.392

 < 0.001

0.344

0.001

 − 0.271

0.007

0.533

 < 0.001

0.405

 < 0.001

 − 0.515

 < 0.001

PLT (× 109/L)

 − 0.201

0.048

0.345

0.001

 − 0.186

0.069

0.329

0.001

0.394

 < 0.001

 − 0.308

0.002

PT (s)

0.154

0.132

 − 0.176

0.085

0.159

0.119

 − 0.207

0.042

 − 0.224

0.028

0.235

0.021

Iron (μmol/L)

NA

NA

 − 0.439

 < 0.001

0.583

 < 0.001

 − 0.859

 < 0.001

 − 0.244

0.016

0.933

 < 0.001

Transferrin (g/L)

 − 0.439

 < 0.001

NA

NA

 − 0.407

 < 0.001

0.698

 < 0.001

0.719

 < 0.001

 − 0.606

 < 0.001

Ferritin (μg/L)

0.583

 < 0.001

 − 0.407

 < 0.001

NA

NA

 − 0.604

 < 0.001

 − 0.328

0.001

0.623

 < 0.001

UIBC (μmol/L)

 − 0.859

 < 0.001

0.698

 < 0.001

 − 0.604

 < 0.001

NA

NA

0.652

 < 0.001

 − 0.965

 < 0.001

TIBC (μmol/L)

 − 0.244

0.016

0.719

 < 0.001

 − 0.328

0.001

0.652

 < 0.001

NA

NA

 − 0.486

 < 0.001

TSI (%)

0.933

 < 0.001

 − 0.606

 < 0.001

0.623

 < 0.001

 − 0.965

 < 0.001

 − 0.486

 < 0.001

NA

NA

Fibrosis stage

0.242

0.017

 − 0.254

0.012

0.395

 < 0.001

 − 0.278

0.006

 − 0.227

0.025

0.292

0.004

  1. NA not applicable
  2. IgG immunoglobulin G, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, TBIL total bilirubin, ALB albumin, PLT platelet, PT prothrombin time, UIBC unsaturated iron binding capacity, TIBC Total iron binding capacity, TSI transferrin saturation index