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Table 2 General characteristics of subjects by liver fibrosis stage

From: Serum ferritin levels are associated with advanced liver fibrosis in treatment-naive autoimmune hepatitis

Variables F0–2 (n = 59) F3–4 (n = 38) P
Age (years) 51.7 ± 11.7 57.5 ± 9.7 0.010
Female, n (%) 50 (84.7) 32 (84.2) 0.943
Autoantibodies positive, n (%) 48 (81.4) 35 (92.1) 0.141
IgG (g/L) 15.00 (12.90, 19.18) 18.70 (15.85, 24.60) 0.002
ALT (U/L) 79.0 (29.0, 387.0) 122.5 (39.8, 311.3) 0.414
AST (U/L) 69.0 (30.0, 387.0) 173.0 (45.8, 421.0) 0.093
ALP (U/L) 101.0 (71.0, 151.0) 118.0 (78.5, 161.0) 0.206
GGT (U/L) 122.0 (73.0, 184.0) 132.0 (54.3, 298.5) 0.444
TBIL (μmol/L) 17.4 (11.8, 33.5) 28.0 (14.8, 134.6) 0.026
ALB (g/L) 41.1 ± 5.0 38.6 ± 6.2 0.035
PLT (× 109/L) 208.5 ± 68.2 148.1 ± 57.5  < 0.001
PT (s) 12.7 ± 1.2 13.9 ± 1.6  < 0.001
Iron (μmol/L) 25.9 ± 16.0 30.5 ± 11.0 0.095
Transferrin (g/L) 2.75 (2.32, 3.25) 2.42 (2.13, 2.88) 0.022
Ferritin (μg/L) 124.0 (43.0, 306.0) 354.0 (189.5, 865.5)  < 0.001
UIBC (μmol/L) 39.3 (23.3, 51.6) 25.0 (16.2, 32.9) 0.005
TIBC (μmol/L) 64.4 (56.1, 72.4) 55.9 (51.7, 61.5) 0.004
TSI (%) 33.8 (22.9, 58.8) 55.1 (42.2, 69.4) 0.005
  1. Data are expressed as mean (± standard deviation), median (quartile 25, quartile 75) or number (proportion)
  2. IgG immunoglobulin G, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, TBIL total bilirubin, ALB albumin, PLT platelet, PT prothrombin time, UIBC unsaturated iron binding capacity, TIBC Total iron binding capacity, TSI transferrin saturation index