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Table 1 General characteristics of the patients with autoimmune hepatitis

From: Serum ferritin levels are associated with advanced liver fibrosis in treatment-naive autoimmune hepatitis

Variables

n = 97

Age (years)

54.0 ± 11.3

Female, n (%)

82 (84.5)

Autoantibodies positive, n (%)

83 (85.6)

ANA + , n (%)

78 (80.4)

ASMA + , n (%)

24 (24.7)

Anti-LKM1 + , n (%)

3 (3.1)

Anti-LC1, n (%)

2 (2.1)

Anti-SLA/LP, n (%)

2 (2.1)

IgG (g/L)

16.80 (13.35, 21.10)

ALT (U/L)

88.0 (32.0, 322.5)

AST (U/L)

113.0 (35.0, 401.0)

ALP (U/L)

110.0 (75.5, 151.0)

GGT (U/L)

125.9 (59.0, 248.0)

TBIL (μmol/L)

20.0 (12.7, 68.4)

ALB (g/L)

40.1 ± 5.6

PLT (× 109/L)

184.8 ± 70.5

PT (s)

13.2 ± 1.5

Iron (μmol/L)

27.7 ± 14.4

Transferrin (g/L)

2.67 (2.28, 3.17)

Ferritin (μg/L)

214.0 (78.0, 515.0)

UIBC (μmol/L)

31.2 (21.2, 48.2)

TIBC (μmol/L)

59.8 (53.8, 68.9)

TSI (%)

43.6 (28.2, 64.2)

AIH score (1999)

15.8 ± 2.7

AIH score (2008)

7.5 ± 1.3

Histology (inflammation), n (%)

 G0

0 (0)

 G1

3 (3.1)

 G2

42 (43.3)

 G3

40 (41.2)

 G4

12 (12.4)

Histology (fibrosis), n (%)

 F0

11 (11.3)

 F1

22 (22.7)

 F2

26 (26.8)

 F3

21 (21.6)

 F4

17 (17.5)

  1. Data are expressed as mean (± standard deviation), median (quartile 25, quartile 75) or number (proportion)
  2. ANA antinuclear antibody, ASMA anti-smooth muscle antibody, Anti-LKM1 anti-liver kidney microsomal antibody type 1, Anti-LC1 anti-liver cytosol type 1 antibody, Anti-SLA/LP anti-soluble liver antigen or anti-liver-pancreas antibodies, IgG immunoglobulin G, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma-glutamyl transpeptidase, TBIL total bilirubin, ALB albumin, PLT platelet, PT prothrombin time, UIBC unsaturated iron binding capacity, TIBC Total iron binding capacity, TSI transferrin saturation index