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Fig. 5 | BMC Gastroenterology

Fig. 5

From: Serum superoxide dismutase level is a potential biomarker of disease prognosis in patients with HEV-induced liver failure

Fig. 5

HEV promotes oxidative stress, HMGB1 release, and then apoptosis in hepatocytes. A Serum from HEV-induced liver diseases led to ROS accumulation in HL-7702 cells; B Serum from HEV-induced liver diseases led to HMGB1 secretion in HL-7702 cells, while inhibited by NAC; C Serum from HEV-induced liver diseases led to apoptosis in HL-7702 cells; D HMGB1 promoted apoptosis in HL-7702 cells. *P < 0.05, **P < 0.01

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