Table 3 Association of the ABCG8 rs11887534 variant and sex with gallstones in the study participants

ABCG8 rs11887534 genotype, sex

 ABCG8 rs11887534 GG, men (reference)

–

–

–

–

 ABCG8 rs11887534 GC + CC, men

1.598

0.941

2.714

0.0827

 ABCG8 rs11887534 GG, women

1.304

1.087

1.565

0.0043

 ABCG8 rs11887534 GC + CC, women

2.291

1.514

3.467

< .0001

Age

1.050

1.042

1.058

< .0001

Regular exercise

 No (reference)

–

–

–

–

 Yes

0.885

0.769

1.020

0.0918

Cigarette smoking

 No (reference)

–

–

–

–

 Yes

1.161

0.950

1.419

0.1448

Alcohol drinking

 No (reference)

–

–

–

–

 Yes

0.997

0.771

1.288

0.9798

BMI

 Normal (reference)

–

–

–

–

 Underweight

0.846

0.506

1.414

0.5239

 Overweight

1.159

0.987

1.360

0.0712

 Obesity

1.104

0.913

1.335

0.3057

Family history of gallstones

 No (reference)

–

–

–

–

 Yes

1.683

1.360

2.083

< .0001

Diabetes

 No (reference)

–

–

–

–

 Yes

1.128

0.927

1.373

0.2302

Total bilirubin

1.823

1.465

2.269

< .0001

AST

0.988

0.977

0.998

0.0213

ALT

1.011

1.005

1.017

0.0004

HDL-C (mg/dL)

0.985

0.979

0.991

< .0001

LDL-C (mg/dL)

0.998

0.996

1.000

0.1123

TG (mg/dL)

0.999

0.998

1.000

0.0592

Dietary fat score

1.000

0.992

1.007

0.8959