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Table 2 Association between the ABCG8 rs11887534 variant and gallstones in the study participants

From: Risk of gallstones based on ABCG8 rs11887534 single nucleotide polymorphism among Taiwanese men and women

Variables OR 95% CI P-value
ABCG8 rs11887534 genotype     
 GG (reference)
 GC + CC 1.698 1.240 2.325 0.0010
Sex     
 Women (reference)
 Men 0.763 0.638 0.913 0.0032
Age 1.050 1.042 1.058 < .0001
Regular exercise     
 No (reference)
 Yes 0.885 0.769 1.020 0.0914
Cigarette smoking     
 No (reference)
 Yes 1.162 0.951 1.420 0.1430
Alcohol drinking     
 No (reference)
 Yes 0.997 0.772 1.289 0.9839
BMI     
 Normal (reference)
 Underweight 0.846 0.506 1.414 0.5238
 Overweight 1.158 0.987 1.359 0.0721
 Obesity 1.105 0.913 1.336 0.3052
Family history of gallstones     
 No (reference)
 Yes 1.683 1.360 2.083 < .0001
Diabetes     
 No (reference)
 Yes 1.128 0.927 1.373 0.2302
Total bilirubin 1.823 1.464 2.269 < .0001
AST 0.988 0.977 0.998 0.0214
ALT 1.011 1.005 1.017 0.0004
HDL-C (mg/dL) 0.985 0.979 0.991 < .0001
LDL-C (mg/dL) 0.998 0.996 1.000 0.1112
TG (mg/dL) 0.999 0.998 1.000 0.0593
Dietary fat score 1.000 0.992 1.007 0.8992
  1. OR odds ratio, CI confidence interval, ABCG8 ATP-binding cassette subfamily G Member 8, BMI body mass index, AST aspartate aminotransferase, ALT alanine transaminase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride