Table 2 Association between the ABCG8 rs11887534 variant and gallstones in the study participants

ABCG8 rs11887534 genotype

 GG (reference)

–

–

–

–

 GC + CC

1.698

1.240

2.325

0.0010

Sex

 Women (reference)

–

–

–

–

 Men

0.763

0.638

0.913

0.0032

Age

1.050

1.042

1.058

< .0001

Regular exercise

 No (reference)

–

–

–

–

 Yes

0.885

0.769

1.020

0.0914

Cigarette smoking

 No (reference)

–

–

–

–

 Yes

1.162

0.951

1.420

0.1430

Alcohol drinking

 No (reference)

–

–

–

–

 Yes

0.997

0.772

1.289

0.9839

BMI

 Normal (reference)

–

–

–

–

 Underweight

0.846

0.506

1.414

0.5238

 Overweight

1.158

0.987

1.359

0.0721

 Obesity

1.105

0.913

1.336

0.3052

Family history of gallstones

 No (reference)

–

–

–

–

 Yes

1.683

1.360

2.083

< .0001

Diabetes

 No (reference)

–

–

–

–

 Yes

1.128

0.927

1.373

0.2302

Total bilirubin

1.823

1.464

2.269

< .0001

AST

0.988

0.977

0.998

0.0214

ALT

1.011

1.005

1.017

0.0004

HDL-C (mg/dL)

0.985

0.979

0.991

< .0001

LDL-C (mg/dL)

0.998

0.996

1.000

0.1112

TG (mg/dL)

0.999

0.998

1.000

0.0593

Dietary fat score

1.000

0.992

1.007

0.8992