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Table 1 Baseline profiles of the study participants stratified by sex

From: Risk of gallstones based on ABCG8 rs11887534 single nucleotide polymorphism among Taiwanese men and women

Variables Women (n = 13,880) Men (n = 7388) P-value
Gallstone    0.1043
 No 13,291 (95.76) 7039 (95.28)  
 Yes 589 (4.24) 349 (4.72)  
ABCG8 rs11887534 genotype    0.4880
 GG 13,462 (96.99) 7178 (97.16)  
 GC + CC 418 (3.01) 210 (2.84)  
Age (years) 49.756 ± 0.088 49.868 ± 0.128 0.4702
Regular exercise    0.0023
 No 8032 (57.87) 4115 (55.70)  
 Yes 5848 (42.13) 3273 (44.30)  
Cigarette smoking    < .0001
 No 13,272 (95.62) 4149 (56.16)  
 Yes 608 (4.38) 3239 (43.84)  
Alcohol drinking    < .0001
 No 13,571 (97.77) 5992 (81.10)  
 Yes 309 (2.23) 1396 (18.90)  
BMI (kg/m2)    < .0001
 18.5 ≤ BMI < 24 (Normal BMI) 7944 (57.23) 2666 (36.09)  
 BMI < 18.5 (Underweight) 531 (3.83) 83 (1.12)  
 24 ≤ BMI < 27 (Overweight) 3280 (23.63) 2698 (36.52)  
 BMI ≥ 27 (Obesity) 2125 (15.31) 1941 (26.27)  
Family history of gallstones    0.0153
 No 12,812 (92.31) 6887 (93.22)  
 Yes 1068 (7.69) 501 (6.78)  
Diabetes    < .0001
 No 12,759 (91.92) 6390 (86.49)  
 Yes 1121 (8.08) 998 (13.51)  
Total bilirubin (mg/dL) 0.6138 ± 0.002 0.7516 ± 0.004 < .0001
AST (U/L) 23.1276 ± 0.100 26.2884 ± 0.173 < .0001
ALT (U/L) 20.8680 ± 0.147 29.9571 ± 0.274 < .0001
HDL-C (mg/dL) 58.3463 ± 0.113 48.1481 ± 0.131 < .0001
LDL-C (mg/dL) 120.7000 ± 0.271 122.3000 ± 0.368 0.0003
TG (mg/dL) 102.3000 ± 0.608 137.000 ± 1.288 < .0001
Dietary fat score 41.7411 ± 0.078 45.9518 ± 0.111 < .0001
Menopause    
 No 6937 (49.98)
 Yes 6943 (50.02)
Hormone use    
 No 11,721 (84.45)
 Yes 2159 (15.55)
  1. Continuous and categorical data are presented as mean ± standard error (SE) and n (%), respectively
  2. n = sample size, ABCG8 ATP-binding cassette subfamily G Member 8, BMI body mass index, AST aspartate aminotransferase, ALT alanine transaminase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride