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Table 2 Bile acid species

From: Hypercortisolism in patients with cholestasis is associated with disease severity

Bile acid species (µmol/L)

Cholestasis group

n = 36

Control group

n = 32

p value

UDCA

0.37 (0.23–0-78)

0.04 (0.02–0.13)

 < 0.001

TUDCA

0.09 (0.04–0.26)

nd

 

TCA

31.9 (3.08–64.04)

0.02 (0.00–0.07)

 < 0.001

TCDCA

15.17 (2.89–26.17)

0.09 (0.03–0.19)

 < 0.001

TDCA

0.16 (0.05–0.60)

nd

 

TLCA

nd

nd

 

GCDCA

22.41 (5.87–34.35)

0.61 (0.29–1.38)

 < 0.001

GCA

55.69 (6.96–92.63)

0.14 (0.05–0.37)

 < 0.001

GDCA

0.36 (0.00–1.29)

0.18 (0.03–0.58)

0.346

GUDCA

0.21 (0.08–0.40)

0.04 (0.00–0.09)

 < 0.001

GLCA

nd

nd

 

UDCA

nd

nd

 

CA

0.04 (0.00–0.11)

0.05 (0.00–0.10)

0.824

CDCA

0.04 (0.00–0.13)

0.05 (0.00–0.11)

0.458

DCA

0.03 (0.00–0-12)

0.23 (0.01–0.40)

0.009

LCA

0.03 (0.00–0.16)

0.04 (0.00–0.06)

0.575

  1. UDCA, ursodeoxycholic acid; TUDCA, tauroursodeoxycholic acid; TCA, taurocholic acid; TCDCA, taurochenodeoxycholic acid; TDCA, taurodeoxycholic acid; TLCA, taurolithocholic acid; GCDCA, glycochenodeoxycholic acid; GCA, glycocholic acid; GDCA, glycodeoxycholic acid; GUDCA, glycoursodeoxycholic acid; GLCA, glycolithocholic acid; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; LCA lithocholic acid; nd, not detected