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Table 2 Characteristics of the four studies about the correlation between Hp and BE dysplasia

From: Helicobacter pylori infection is associated with reduced risk of Barrett’s esophagus: a meta-analysis and systematic review

Authors Years Journal Hp testing method Biopsy location BE Cases Hp +  Total Controls Hp +  Total
Aghayeva et al. [36] 2019 Dis Esophagus H*, R† Antrum IM‡ BE with dysplasia 5 11 BE without dysplasia 48 72
Sonnenberg et al. [11] 2017 Aliment Pharmacol Ther H Stomach IM BE without dysplasia or cancer 1972 76,475 Endoscopy 20,683 284,552
       BE with dysplasia or cancer 138 6167 Endoscopy 20,683 284,552
Thrift et al. [57] 2012 Int J Cancer S§   IM BE 28 296 Population 73 390
       BE without dysplasia 25 208 Population 73 390
       BE with dysplasia 3 88 Population 73 390
Vieth et al. [65] 2000 Digestion H Antrum, Corpus IM BE 463 1054 NUD 378 712
       Barrett’s neoplasia (HGD|| or adenocarcinoma) 54 138 NUD 378 712
  1. *: Histology, †: Rapid ureas e t est, ‡: Intestinal metaplasia, §: Serology, ||: High dysplasia
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BMC Gastroenterology

ISSN: 1471-230X

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