Table 1 Characteristics of the patients (N = 353)
Variable | Total (n = 353) | Dysbacteriosis grade 1 (n = 268) | Dysbacteriosis grade 2 (n = 58) | Dysbacteriosis grade 3 (n = 27) | F/x2 | P |
|---|---|---|---|---|---|---|
Age (years), Mean ± SD (range) | 60.7 ± 12.6 (21–88) | 60.5 ± 12.9 (21–88) | 61.4 ± 12.1 (31–86) | 60.7 ± 10.9 (43–79) | 0.120 | 0.887 |
Sex, N(%) | Â | Â | Â | Â | 2.124 | 0.351 |
 Male | 150 (42.5%) | 110 (41.0%) | 25 (43.1%) | 15 (55.6%) |  |  |
 Female | 203 (57.5%) | 158 (59.0%) | 33 (56.9%) | 12 (44.4%) |  |  |
Tumour location, N(%) | Â | Â | Â | Â | 7.282 | 0.026 |
 Rectum | 204 (57.8%) | 160 (59.7%) | 25 (43.1%) | 19 (70.4%) |  |  |
 Colon | 149 (42.2%) | 108 (40.3%) | 33 (56.9%) | 8 (29.6%) |  |  |
BMI (kg/m2)†, N(%) |  |  |  |  | 3.524 | 0.710§ |
 Underweight (< 18.5) | 24 (6.8%) | 16 (6.0%) | 5 (8.6%) | 3 (11.1%) |  |  |
 Normal (18.5–24.9) | 246 (69.7%) | 184 (68.7%) | 43 (74.1%) | 19 (70.4%) |  |  |
 Overweight (25.0–29.9) | 80 (22.7%) | 65 (24.3%) | 10 (17.2%) | 5 (18.5%) |  |  |
 Obese (≥ 30.0) | 3 (0.8%) | 3 (1.1%) | 0 (0.0%) | 0 (0.0%) |  |  |
Comorbidities‡, N(%) |  |  |  |  |  |  |
 Cardiopulmonary disease | 39 (11.0%) | 34 (12.7%) | 3 (5.2%) | 2 (7.4%) | 3.134 | 0.209 |
 Diabetes | 26 (7.4%) | 19 (7.1%) | 4 (6.9%) | 3 (11.1%) | 0.604 | 0.739 |
 Liver or kidney disease | 12 (3.4%) | 9 (3.4%) | 1 (1.7%) | 2 (7.4%) | 1.913 | 0.409§ |
 Preoperative anaemia | 136 (38.5%) | 96 (35.8%) | 26 (44.8%) | 14 (51.9%) | 3.825 | 0.146 |
Preoperative albumin (g/L), Mean ± SD | 42.39 ± 4.97 | 42.63 ± 4.66 | 42.18 ± 6.14 | 40.44 ± 4.95 | 2.436 | 0.089 |
Neoadjuvant therapy, N(%) | 77 (21.8%) | 65 (24.3%) | 7 (12.1%) | 5 (18.5%) | 4.337 | 0.111 |
ASA score, N(%) |  |  |  |  | 8.330 | 0.198 § |
 1 | 7 (2.0%) | 3 (1.1%) | 3 (5.2%) | 1 (3.7%) |  |  |
 2 | 271 (76.8%) | 211 (78.7%) | 42 (72.4%) | 18 (66.7%) |  |  |
 3 | 74 (21.0%) | 53 (19.8%) | 13 (22.4%) | 8 (29.6%) |  |  |
 4 | 1 (0.3%) | 1 (0.4%) | 0 | 0 |  |  |
TNM stage, N(%) | Â | Â | Â | Â | 8.295 | 0.217 |
 I | 67 (19.0%) | 48 (17.9%) | 14 (24.1%) | 5 (18.5%) |  |  |
 II | 118 (33.4%) | 86 (32.1%) | 23 (39.7%) | 9 (33.3%) |  |  |
 III | 147 (41.6%) | 120 (44.8%) | 15 (25.9%) | 12 (44.4%) |  |  |
 IV | 21 (5.9%) | 14 (5.2%) | 6 (10.3%) | 1 (3.7%) |  |  |
Surgical approach, N(%) | Â | Â | Â | Â | 1.203 | 0.548 |
 Open abdominal | 86 (24.4%) | 69 (25.7%) | 12 (20.7%) | 5 (18.5%) |  |  |
 Laparoscopic | 267 (75.6%) | 199 (74.3%) | 46 (79.3%) | 22 (81.5%) |  |  |
Operation time, N(%) | Â | Â | Â | Â | 0.844 | 0.656 |
 < 3 h | 100 (28.3%) | 79 (29.5%) | 15 (25.9%) | 6 (22.2%) |  |  |
 ≥ 3 h | 253 (71.7%) | 189 (70.5%) | 43 (74.1%) | 21 (77.8%) |  |  |
Intraoperative blood loss (ml), Median (IQR) | 50 (30–80) | 50 (30–80) | 50 (30–60) | 50 (30–100) | 2.639 | 0.267 |
Mechanical bowel preparation, N(%) | 214 (60.6%) | 162 (60.4%) | 33 (56.9%) | 19 (70.4%) | 1.415 | 0.493 |