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Table 3 Histopathological findings in the patients with undifferentiated gastric cancer according to Helicobacter pylori infection status

From: Effect of Helicobacter pylori infection on malignancy of undifferentiated-type gastric cancer

 

UD-E (A)

UD-I (B)

UD-U (C)

Significance

Maximum lesion diameter, mean ± SD

19.3 ± 11.7

18.6 ± 10.2

10.1 ± 5.4

P < 0.01 (A vs B vs C)

p = 0.001 (C vs A)

p = 0.005 (B vs C)

NS (A vs B)

Pathological type, % of pure signet ring cell CA

50.0% (14/28)

28.9% (11/38)

87.5% (21/24)

p < 0.001 (A vs B vs C)

p < 0.001 (B vs C, C vs A)

NS (A vs B)

Depth, % of SM invasive cancer

14.3% (4/28)

10.5% (4/38)

0% (0/24)

NS (A vs B vs C)

NS (A vs B, B vs C, C vs A)

Lymphovascular invasion, % of undifferentiated CA

10.7% (3/28)

0% (0/38)

0% (0/24)

NS (A vs B vs C)

NS (A vs B, B vs C, C vs A)

  1. CA, carcinoma; NS, not statistically significant; SD, standard deviation; SM, submucosal; UD-E, post-eradication group: UD-I, current infection group; UD-U, non-infected group