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Table 2 Comparison of concentration of SCFA in faeces between patients in the two groups

From: Dietary triggers of gut inflammation following exclusive enteral nutrition in children with Crohn’s disease: a pilot study

SCFA

Group A (n = 6)

Group B (n = 7)

p value

p value adj

Faecal water content (%)

74 (70, 80.5)

73.2 (65.7, 80)

0.601

0.340

Acetate (µmol/g)

255 (238, 341)

304 (223, 385)

0.716

0.959

Propionate (µmol/g)

80.5 (70.5, 143)

72.1 (46.3, 109)

0.367

0.126

Isobutyrate (µmol/g)

10.9 (7.6, 16.7)

8.70 (6.1, 9.9)

0.121

0.174

Butyrate (µmol/g)

62.5 (41.8, 114)

34.1 (29.2, 49.6)

0.016

0.015

Isovalerate (µmol/g)

11.4 (7, 17.4)

8.6 (4.8, 11.7)

0.180

0.297

Total SCFA (µmol/g)

401 (386, 663)

395 (344, 537)

0.533

0.255

Acetate (%)

60.2 (56.7, 65.2)

71.6 (60.2, 75.4)

0.037

0.027

Propionate (%)

20.6 (18, 21.4)

18.7 (12.4, 20.9)

0.450

0.208

Isobutyrate (%)

2.2 (2.02, 3.4)

1.9 (1.4, 2.5)

0.163

0.355

Butyrate (%)

15.1 (11.2, 17.8)

8.6 (8.6, 9.1)

0.008

0.016

Isovalerate (%)

2.1 (1.9, 3.8)

1.8 (1.2, 3.1)

0.295

0.598

  1. Group A: patients with faecal calprotectin levels above the median levels at food reintroduction, Group B: patients with faecal calprotectin values below the median levels at food reintroduction. Values are presented as medians (Q1, Q3). p value adj: p value adjusted for faecal calprotectin levels at the end of EEN. %: proportional ratio of each SCFA to total SCFA; SCFA: Short chain fatty acids