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Table 2 Comparison of concentration of SCFA in faeces between patients in the two groups

From: Dietary triggers of gut inflammation following exclusive enteral nutrition in children with Crohn’s disease: a pilot study

SCFA Group A (n = 6) Group B (n = 7) p value p value adj
Faecal water content (%) 74 (70, 80.5) 73.2 (65.7, 80) 0.601 0.340
Acetate (µmol/g) 255 (238, 341) 304 (223, 385) 0.716 0.959
Propionate (µmol/g) 80.5 (70.5, 143) 72.1 (46.3, 109) 0.367 0.126
Isobutyrate (µmol/g) 10.9 (7.6, 16.7) 8.70 (6.1, 9.9) 0.121 0.174
Butyrate (µmol/g) 62.5 (41.8, 114) 34.1 (29.2, 49.6) 0.016 0.015
Isovalerate (µmol/g) 11.4 (7, 17.4) 8.6 (4.8, 11.7) 0.180 0.297
Total SCFA (µmol/g) 401 (386, 663) 395 (344, 537) 0.533 0.255
Acetate (%) 60.2 (56.7, 65.2) 71.6 (60.2, 75.4) 0.037 0.027
Propionate (%) 20.6 (18, 21.4) 18.7 (12.4, 20.9) 0.450 0.208
Isobutyrate (%) 2.2 (2.02, 3.4) 1.9 (1.4, 2.5) 0.163 0.355
Butyrate (%) 15.1 (11.2, 17.8) 8.6 (8.6, 9.1) 0.008 0.016
Isovalerate (%) 2.1 (1.9, 3.8) 1.8 (1.2, 3.1) 0.295 0.598
  1. Group A: patients with faecal calprotectin levels above the median levels at food reintroduction, Group B: patients with faecal calprotectin values below the median levels at food reintroduction. Values are presented as medians (Q1, Q3). p value adj: p value adjusted for faecal calprotectin levels at the end of EEN. %: proportional ratio of each SCFA to total SCFA; SCFA: Short chain fatty acids