|
Factor
|
Category
|
Univariate
|
Multivariate
|
|---|
|
Hazard ratio
|
(95% CI)
|
P value*
|
Hazard ratio
|
(95% CI)
|
P value*
|
|---|
|
FIB-4 index
|
< 2.67
|
1
| | |
1
| | |
| |
≥ 2.67
|
17.5
|
(4.49–67.8)
|
< 0.001
|
23.2
|
(5.66–95.1)
|
< 0.001
|
|
Gamma-glutamyl transpeptidase
|
< 219 U/L
|
1
| | |
1
| | |
| |
≥ 219 U/L
|
3.45
|
(1.11–10.7)
|
0.032
|
5.53
|
(1.70–18.0)
|
0.004
|
- *Significance was determined using the Cox proportional hazard model. Variables that were statistically significant on univariate analysis were entered into multivariate analysis to identify significant independent factors. The characteristics of the 432 patients who were confirmed to have no previous or current liver-related events at NAFLD diagnosis were evaluated for the rate of development of liver-related events. During the follow-up period, 13 patients developed liver-related events. Liver-related events included liver cancer, hepatic encephalopathy, esophago-gastric varices, ascites, and jaundice
