Fig. 1

Time to COVID-19 hospitalization (panel A) and the development of severe COVID-19 (panel B), among patients with chronic liver disease (n = 42,320) and population controls (n = 182,147), matched at the index date¹. ¹Index date was defined as the date of index liver biopsy among patients with chronic liver disease or the equivalent matching date among population controls (see “Methods” for details). Subjects were matched by age, sex, calendar year and county of residence, and follow-up began on February 1, 2020. ²For definitions of COVID-19 hospitalization and development of severe COVID-19, see “Methods” and Additional file 1: Table S3