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Table 2 Sub-distribution hazard ratio (sHR) of characteristics for cancer-specific death in univariate and multivariate competing risk models

From: Impact of chemotherapy and radiotherapy on the survival of elderly esophageal cancer patients undergoing surgery: a SEER database analysis

Characteristics Univariate analysis Multivariate analysis
sHR 95% CI P value sHR 95% CI P value
Race       
 White 1 (Ref)      
 Other racesa 1.21 0.85–1.72 0.29    
Sex       
 Male 1 (Ref)      
 Female 1.09 0.85–1.4 0.5    
Marriage       
 Unmarried 1 (Ref)      
 Married 1.06 0.83–1.34 0.65    
Location       
 Upper third 1 (Ref)      
 Middle third 1.1 0.55–2.18 0.8    
 Low third 0.82 0.42–1.58 0.55    
Histology       
 Adenocarcinoma 1 (Ref)      
 SCC 1.1 0.85–1.42 0.46    
Gradeb       
 I + II 1 (Ref)    1 (Ref)   
 III + IV 1.93 1.56–2.4 < 0.001 1.57 1.26–1.96 < 0.001
Size       
 < 33 mm 1 (Ref)    1 (Ref)   
 ≥ 33 mm 2.14 1.71–2.68 < 0.001 1.34 1.04–1.75 0.026
T stage       
 T1 1 (Ref)    1 (Ref)   
 T2 1.95 1.35–2.81 < 0.001 1.5 1.01–2.22 0.046
 T3 3.12 2.33–4.18 < 0.001 1.95 1.36–2.81 < 0.001
 T4 6.14 3.8–9.93 < 0.001 3.3 1.88–5.76 < 0.001
Lymph node       
 Negative 1 (Ref)    1 (Ref)   
 Positive 2.45 1.96–3.06 < 0.001 1.51 1.17–1.96 0.002
Metastasis       
 No 1 (Ref)    1 (Ref)   
 Yes 2.58 1.64–4.06 < 0.001 1.68 1.07–2.65 0.024
  1. CI confidence interval, SCC squamous cell carcinoma
  2. aOther races: Black, American Indian/Alaska Native, Asian/Pacific Islander
  3. bI: well differentiation; II: moderate differentiation; III: poor differentiation; IV: undifferentiation