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Table 2 Sub-distribution hazard ratio (sHR) of characteristics for cancer-specific death in univariate and multivariate competing risk models

From: Impact of chemotherapy and radiotherapy on the survival of elderly esophageal cancer patients undergoing surgery: a SEER database analysis

Characteristics

Univariate analysis

Multivariate analysis

sHR

95% CI

P value

sHR

95% CI

P value

Race

      

 White

1 (Ref)

     

 Other racesa

1.21

0.85–1.72

0.29

   

Sex

      

 Male

1 (Ref)

     

 Female

1.09

0.85–1.4

0.5

   

Marriage

      

 Unmarried

1 (Ref)

     

 Married

1.06

0.83–1.34

0.65

   

Location

      

 Upper third

1 (Ref)

     

 Middle third

1.1

0.55–2.18

0.8

   

 Low third

0.82

0.42–1.58

0.55

   

Histology

      

 Adenocarcinoma

1 (Ref)

     

 SCC

1.1

0.85–1.42

0.46

   

Gradeb

      

 I + II

1 (Ref)

  

1 (Ref)

  

 III + IV

1.93

1.56–2.4

< 0.001

1.57

1.26–1.96

< 0.001

Size

      

 < 33 mm

1 (Ref)

  

1 (Ref)

  

 ≥ 33 mm

2.14

1.71–2.68

< 0.001

1.34

1.04–1.75

0.026

T stage

      

 T1

1 (Ref)

  

1 (Ref)

  

 T2

1.95

1.35–2.81

< 0.001

1.5

1.01–2.22

0.046

 T3

3.12

2.33–4.18

< 0.001

1.95

1.36–2.81

< 0.001

 T4

6.14

3.8–9.93

< 0.001

3.3

1.88–5.76

< 0.001

Lymph node

      

 Negative

1 (Ref)

  

1 (Ref)

  

 Positive

2.45

1.96–3.06

< 0.001

1.51

1.17–1.96

0.002

Metastasis

      

 No

1 (Ref)

  

1 (Ref)

  

 Yes

2.58

1.64–4.06

< 0.001

1.68

1.07–2.65

0.024

  1. CI confidence interval, SCC squamous cell carcinoma
  2. aOther races: Black, American Indian/Alaska Native, Asian/Pacific Islander
  3. bI: well differentiation; II: moderate differentiation; III: poor differentiation; IV: undifferentiation
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BMC Gastroenterology

ISSN: 1471-230X

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