|
Characteristics
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
sHR
|
95% CI
|
P value
|
sHR
|
95% CI
|
P value
|
|---|
|
Race
| | | | | | |
|
White
|
1 (Ref)
| | | | | |
|
Other racesa
|
1.21
|
0.85–1.72
|
0.29
| | | |
|
Sex
| | | | | | |
|
Male
|
1 (Ref)
| | | | | |
|
Female
|
1.09
|
0.85–1.4
|
0.5
| | | |
|
Marriage
| | | | | | |
|
Unmarried
|
1 (Ref)
| | | | | |
|
Married
|
1.06
|
0.83–1.34
|
0.65
| | | |
|
Location
| | | | | | |
|
Upper third
|
1 (Ref)
| | | | | |
|
Middle third
|
1.1
|
0.55–2.18
|
0.8
| | | |
|
Low third
|
0.82
|
0.42–1.58
|
0.55
| | | |
|
Histology
| | | | | | |
|
Adenocarcinoma
|
1 (Ref)
| | | | | |
|
SCC
|
1.1
|
0.85–1.42
|
0.46
| | | |
|
Gradeb
| | | | | | |
|
I + II
|
1 (Ref)
| | |
1 (Ref)
| | |
|
III + IV
|
1.93
|
1.56–2.4
|
< 0.001
|
1.57
|
1.26–1.96
|
< 0.001
|
|
Size
| | | | | | |
|
< 33 mm
|
1 (Ref)
| | |
1 (Ref)
| | |
|
≥ 33 mm
|
2.14
|
1.71–2.68
|
< 0.001
|
1.34
|
1.04–1.75
|
0.026
|
|
T stage
| | | | | | |
|
T1
|
1 (Ref)
| | |
1 (Ref)
| | |
|
T2
|
1.95
|
1.35–2.81
|
< 0.001
|
1.5
|
1.01–2.22
|
0.046
|
|
T3
|
3.12
|
2.33–4.18
|
< 0.001
|
1.95
|
1.36–2.81
|
< 0.001
|
|
T4
|
6.14
|
3.8–9.93
|
< 0.001
|
3.3
|
1.88–5.76
|
< 0.001
|
|
Lymph node
| | | | | | |
|
Negative
|
1 (Ref)
| | |
1 (Ref)
| | |
|
Positive
|
2.45
|
1.96–3.06
|
< 0.001
|
1.51
|
1.17–1.96
|
0.002
|
|
Metastasis
| | | | | | |
|
No
|
1 (Ref)
| | |
1 (Ref)
| | |
|
Yes
|
2.58
|
1.64–4.06
|
< 0.001
|
1.68
|
1.07–2.65
|
0.024
|
- CI confidence interval, SCC squamous cell carcinoma
- aOther races: Black, American Indian/Alaska Native, Asian/Pacific Islander
- bI: well differentiation; II: moderate differentiation; III: poor differentiation; IV: undifferentiation
