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Table 1 Characteristics of subjects by tertiles of serum FT3 level

From: Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults

Variables

Tertile 1

Tertile 2

Tertile 3

Total

P value

N (%)

29 (33.0%)

30 (34.0%)

29 (33.0%)

88 (100.0%)

 

Male gender

2 (6.9%)

5 (16.7%)

17 (58.6%)

24 (27.3%)

 < 0.001*

Age (years)

32.2 ± 7.2

29.3 ± 7.4

27.2 ± 5.8

30.0 ± 7.2

0.024*

Ever drinking (n, %)

1 (3.4%)

2 (6.7%)

6 (20.7%)

9 (10.2%)

0.070

BMI (kg/m2)

27.9 (26.3–31.3)

29.4 (27.8–32.5)

33.5 (30.6–36.5)

30.0 (27.7–33.4)

 < 0.001*

Waist circumference (cm)

91.3 ± 8.4

96.0 ± 10.1

106.1 ± 11.8

97.2 ± 11.8

 < 0.001*

WHtR

0.56 ± 0.04

0.59 ± 0.05

0.63 ± 0.07

0.59 ± 0.06

 < 0.001*

Systolic blood pressure (mmHg)

118.5 ± 10.8

121.0 ± 11.3

128.3 ± 17.5

122.6 ± 14.0

0.019*

Diastolic blood pressure (mmHg)

80.5 ± 8.7

80.9 ± 9.1

80.9 ± 12.3

80.8 ± 10.0

0.986

FPG (mmol/L)

5.06(4.60–5.42)

4.86(4.61–5.42)

5.14(4.56–5.31)

4.97(4.59–5.35)

0.813

Fasting insulin (pmol/L)

101.8 (82.7–138.2)

120.4 (91.8–158.6)

162.7 (122.8–222.9)

128.3 (91.2–180.9)

0.002*

HOMA-IR

3.25 (2.62–4.55)

3.96 (3.03–5.52)

5.20 (3.83–6.56)

4.03 (3.06–5.85)

0.002*

Triglyceride (mmol/L)

1.36 (1.14–2.26)

1.64 (1.29–2.15)

1.84 (1.58–2.82)

1.63 (1.27–2.54)

0.054

Total cholesterol (mmol/L)

5.27 ± 1.05

4.96 ± 0.84

5.14 ± 0.94

5.14 ± 0.96

0.481

HDL-cholesterol (mmol/L)

1.33 ± 0.29

1.15 ± 0.27

1.23 ± 0.23

1.23 ± 0.27

0.039*

LDL-cholesterol (mmol/L)

3.17 ± 0.74

2.96 ± 0.71

3.08 ± 0.84

3.08 ± 0.78

0.600

FT3 (pmol/L)

4.76 (4.61–4.87)

5.15 (5.10–5.28)

5.95 (5.58–6.36)

5.15 (4.87–5.61)

 < 0.001*

FT4 (pmol/L)

15.75 ± 2.41

17.47 ± 2.13

17.94 ± 2.57

17.06 ± 2.53

0.002*

TSH (mIU/L)

2.50 (1.41–3.31)

2.23 (1.52–2.90)

2.09 (1.40–2.80)

2.24 (1.48–2.98)

0.573

FLI score

47.7 (33.9–60.8)

61.5 (45.1–88.9)

90.5 (84.5–94.8)

69.3 (46.0–90.9)

 < 0.001*

CAP (dB/m)

295.4 ± 44.1

290.1 ± 68.2

331.7 ± 43.6

305.0 ± 55.0

0.007*

  1. Data were presented as mean ± SD or median (interquartile ranges) for continuous variables, and numbers (proportions) for categorical variables
  2. SBP systolic pressure, DBP diastolic pressure, WC waist circumference, BMI body mass index, WHtR waist-to-height ratio, FPG fasting plasma glucose, HOMA-IR homeostatic model assessment of insulin resistance, TC total cholesterol, TG triglycerides, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol, FT3 free triodothyronine, FT4 free thyroxine, TSH thyroid stimulating hormone, FLI Fatty Liver Index, CAP controlled attenuation parameter
  3. *p < 0.05
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BMC Gastroenterology

ISSN: 1471-230X

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