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Table 1 Characteristics of subjects by tertiles of serum FT3 level

From: Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults

Variables Tertile 1 Tertile 2 Tertile 3 Total P value
N (%) 29 (33.0%) 30 (34.0%) 29 (33.0%) 88 (100.0%)  
Male gender 2 (6.9%) 5 (16.7%) 17 (58.6%) 24 (27.3%)  < 0.001*
Age (years) 32.2 ± 7.2 29.3 ± 7.4 27.2 ± 5.8 30.0 ± 7.2 0.024*
Ever drinking (n, %) 1 (3.4%) 2 (6.7%) 6 (20.7%) 9 (10.2%) 0.070
BMI (kg/m2) 27.9 (26.3–31.3) 29.4 (27.8–32.5) 33.5 (30.6–36.5) 30.0 (27.7–33.4)  < 0.001*
Waist circumference (cm) 91.3 ± 8.4 96.0 ± 10.1 106.1 ± 11.8 97.2 ± 11.8  < 0.001*
WHtR 0.56 ± 0.04 0.59 ± 0.05 0.63 ± 0.07 0.59 ± 0.06  < 0.001*
Systolic blood pressure (mmHg) 118.5 ± 10.8 121.0 ± 11.3 128.3 ± 17.5 122.6 ± 14.0 0.019*
Diastolic blood pressure (mmHg) 80.5 ± 8.7 80.9 ± 9.1 80.9 ± 12.3 80.8 ± 10.0 0.986
FPG (mmol/L) 5.06(4.60–5.42) 4.86(4.61–5.42) 5.14(4.56–5.31) 4.97(4.59–5.35) 0.813
Fasting insulin (pmol/L) 101.8 (82.7–138.2) 120.4 (91.8–158.6) 162.7 (122.8–222.9) 128.3 (91.2–180.9) 0.002*
HOMA-IR 3.25 (2.62–4.55) 3.96 (3.03–5.52) 5.20 (3.83–6.56) 4.03 (3.06–5.85) 0.002*
Triglyceride (mmol/L) 1.36 (1.14–2.26) 1.64 (1.29–2.15) 1.84 (1.58–2.82) 1.63 (1.27–2.54) 0.054
Total cholesterol (mmol/L) 5.27 ± 1.05 4.96 ± 0.84 5.14 ± 0.94 5.14 ± 0.96 0.481
HDL-cholesterol (mmol/L) 1.33 ± 0.29 1.15 ± 0.27 1.23 ± 0.23 1.23 ± 0.27 0.039*
LDL-cholesterol (mmol/L) 3.17 ± 0.74 2.96 ± 0.71 3.08 ± 0.84 3.08 ± 0.78 0.600
FT3 (pmol/L) 4.76 (4.61–4.87) 5.15 (5.10–5.28) 5.95 (5.58–6.36) 5.15 (4.87–5.61)  < 0.001*
FT4 (pmol/L) 15.75 ± 2.41 17.47 ± 2.13 17.94 ± 2.57 17.06 ± 2.53 0.002*
TSH (mIU/L) 2.50 (1.41–3.31) 2.23 (1.52–2.90) 2.09 (1.40–2.80) 2.24 (1.48–2.98) 0.573
FLI score 47.7 (33.9–60.8) 61.5 (45.1–88.9) 90.5 (84.5–94.8) 69.3 (46.0–90.9)  < 0.001*
CAP (dB/m) 295.4 ± 44.1 290.1 ± 68.2 331.7 ± 43.6 305.0 ± 55.0 0.007*
  1. Data were presented as mean ± SD or median (interquartile ranges) for continuous variables, and numbers (proportions) for categorical variables
  2. SBP systolic pressure, DBP diastolic pressure, WC waist circumference, BMI body mass index, WHtR waist-to-height ratio, FPG fasting plasma glucose, HOMA-IR homeostatic model assessment of insulin resistance, TC total cholesterol, TG triglycerides, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol, FT3 free triodothyronine, FT4 free thyroxine, TSH thyroid stimulating hormone, FLI Fatty Liver Index, CAP controlled attenuation parameter
  3. *p < 0.05