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Table 1 PTTM cases of early or micro-occult gastric cancer undetectable on endoscopy or macroscopic postmortem examination

From: Pulmonary tumor thrombotic microangiopathy in occult early gastric cancer that was undetectable on upper endoscopy: a case report and review of similar cases

Case no References Age and sex Type Maximum diameter (mm) Invasion depth Endoscopic findings Initial pathological method for confirming cancer Initial method for identifying cancer in the stomach Other clinical findings Pharmacotherapy
1 Sato [3] 50M Sig + tub 30 Early (SM) An ulcerated lesion Biopsy of the stomach Endoscopy Metastasis of cervical lymph nodes, skin, and multiple bones 5-FU + MMC + CDDP (death on the 86th hospital day)
2 Igarashi [4, 5] 29F Sig 20 Early (M) Not performed Autopsy Autopsy (macroscopy) 18 weeks of pregnancy; metastasis of multiple lymph node, bone marrow, and ovaries AC (death on the 5th hospital day)
3 Hara [7] 17M Sig 4 Early (M) Not performed Autopsy Autopsy (microscopy on multiple sections) Bilateral hilar lymphadenopathy Details unknown
4 Yasui [8] 56M Sig 15 Early (M) Normal Biopsy of cervical lymph node Autopsy (microscopy on multiple sections) Elevated tumor markers; cervical, mediastinal, hilar, and abdominal lymphadenopathy CBDCA + PTX (death on the next day after CTx started)
5 Sato [6] 43M Sig ND Early ND ND ND ND AC
6 Sato [6] 68F Sig ND Early ND ND ND ND AC, etc. (details unknown)
7 Sato [6] 74M Por + tub ND Early ND ND ND ND CTx (details unknown)
8 Sato [6] 64F Sig ND Early ND ND ND ND Details unknown
9 Sato [6] 62F Sig ND Early ND ND ND ND Details unknown
10 Sato [6] 50M Por + sig ND Early ND ND ND ND CTx (details unknown)
11 Sato [6] 51F Sig + tub + pap ND Early ND ND ND ND Details unknown
12 Tateishi [9] 75M Sig 1.8 Advanced Normal TBNA of mediastinal lymph node, TBLB Autopsy (microscopy on multiple sections) Mediastinal lymphadenopathy CBDCA + PTX; AC (death on the 28th day after CTx started)
13 Present case 50M Sig 15, 8 Early (M) Normal Needle biopsy of cervical lymph node Autopsy (microscopy on multiple sections) Elevated tumor markers; cervical, mediastinal, hilar, and upper abdominal lymphadenopathy SOX; imatinib; AC; CS (death on the next day after SOX and imatinib started)
  1. PTTM pulmonary tumor thrombotic microangiopathy, SM submucosa, M mucosa, 5-FU 5-fluorouracil, MMC mitomycin C, CDDP cisplatin, AC anticoagulation, ND no data, CTx chemotherapy, sig signet ring cell carcinoma, por poorly differentiated adenocarcinoma, tub tubular adenocarcinoma, pap papillary adenocarcinoma, TBNA transbronchial needle aspiration, TBLB transbronchial lung biopsy, CBDCA carboplatin, PTX paclitaxel, SOX tegafur/gimeracil/oteracil plus oxaliplatin, CS corticosteroid