Table 1 PTTM cases of early or micro-occult gastric cancer undetectable on endoscopy or macroscopic postmortem examination
Case no | References | Age and sex | Type | Maximum diameter (mm) | Invasion depth | Endoscopic findings | Initial pathological method for confirming cancer | Initial method for identifying cancer in the stomach | Other clinical findings | Pharmacotherapy |
|---|---|---|---|---|---|---|---|---|---|---|
1 | Sato [3] | 50M | Sig + tub | 30 | Early (SM) | An ulcerated lesion | Biopsy of the stomach | Endoscopy | Metastasis of cervical lymph nodes, skin, and multiple bones | 5-FU + MMC + CDDP (death on the 86th hospital day) |
2 | 29F | Sig | 20 | Early (M) | Not performed | Autopsy | Autopsy (macroscopy) | 18Â weeks of pregnancy; metastasis of multiple lymph node, bone marrow, and ovaries | AC (death on the 5th hospital day) | |
3 | Hara [7] | 17M | Sig | 4 | Early (M) | Not performed | Autopsy | Autopsy (microscopy on multiple sections) | Bilateral hilar lymphadenopathy | Details unknown |
4 | Yasui [8] | 56M | Sig | 15 | Early (M) | Normal | Biopsy of cervical lymph node | Autopsy (microscopy on multiple sections) | Elevated tumor markers; cervical, mediastinal, hilar, and abdominal lymphadenopathy | CBDCA + PTX (death on the next day after CTx started) |
5 | Sato [6] | 43M | Sig | ND | Early | ND | ND | ND | ND | AC |
6 | Sato [6] | 68F | Sig | ND | Early | ND | ND | ND | ND | AC, etc. (details unknown) |
7 | Sato [6] | 74M | Por + tub | ND | Early | ND | ND | ND | ND | CTx (details unknown) |
8 | Sato [6] | 64F | Sig | ND | Early | ND | ND | ND | ND | Details unknown |
9 | Sato [6] | 62F | Sig | ND | Early | ND | ND | ND | ND | Details unknown |
10 | Sato [6] | 50M | Por + sig | ND | Early | ND | ND | ND | ND | CTx (details unknown) |
11 | Sato [6] | 51F | Sig + tub + pap | ND | Early | ND | ND | ND | ND | Details unknown |
12 | Tateishi [9] | 75M | Sig | 1.8 | Advanced | Normal | TBNA of mediastinal lymph node, TBLB | Autopsy (microscopy on multiple sections) | Mediastinal lymphadenopathy | CBDCA + PTX; AC (death on the 28th day after CTx started) |
13 | Present case | 50M | Sig | 15, 8 | Early (M) | Normal | Needle biopsy of cervical lymph node | Autopsy (microscopy on multiple sections) | Elevated tumor markers; cervical, mediastinal, hilar, and upper abdominal lymphadenopathy | SOX; imatinib; AC; CS (death on the next day after SOX and imatinib started) |