Fig. 3

Performance of NLR and lactate in assessment of ACLF progression and BI status was compared in 290 patients with HBV-ACLF in the derivation cohort. a Comparison of baseline values of NLR among three patient subgroups (ACLF-1, n = 70; ACLF-2, n = 139; ACLF-3, n = 81); b Comparison of baseline values of lactate among the above-mentioned three subgroups; c Comparison of baseline values of NLR among four patient subgroups (without LC or BI, n = 43; without LC and with BI, n = 24; with LC and without BI, n = 86; with LC and with BI, n = 137); d Comparison of baseline values of lactate among the above-mentioned four patient subgroups. Continuous data are expressed using median (IQR) and compared using the Kruskal–Wallis test. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. ACLF was graded per the AARC ACLF score (5–7; 8–10; 11–15). Abbreviations: NLR, neutrophil-to-lymphocyte ratio; LC, liver cirrhosis; BI, bacterial infection; ACLF, acute-on-chronic liver failure; HBV-ACLF, hepatitis b related ACLF; AARC, Asian Pacific Society for the Study of the Liver ACLF research consortium