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Table 2 Association of clinical parameters and prognostic scoring systems with serum suPAR concentrations

From: Soluble urokinase plasminogen activator receptor is associated with short-term mortality and enhanced reactive oxygen species production in acute-on-chronic liver failure

Variable

Correlation coefficient with serum suPAR (r)

p value

Number of patients

Age

0.203**

0.001

282

Infection-immunity data

   

 Bacterial or fungal infection

0.118*

0.04

282

 HBcAb

 − 0.182**

0.003

261

 WBC

0.306***

 < 0.001

282

  Neutrophil (%)

0.250***

 < 0.001

271

Monocyte (%)

0.065

0.28

271

 Lymphocyte (%)

 − 0.327***

 < 0.001

271

 PCT

0.205**

0.008

166

 CPR

0.055

0.39

215

 MIP1beta

0.453**

0.007

40

 IL8

0.448**

0.003

40

Liver-related data

   

 ALT

0.036

0.55

282

 Albumin

 − 0.098

0.101

282

 Bilirubin

0.287***

 < 0.001

282

 INR

0.281***

 < 0.001

282

Heart-related data

   

 MAP

 − 0.015

0.80

282

 hsTnI

0.161

0.080

119

Kidney-related data

   

 GFR

 − 0.290***

 < 0.001

270

 Creatinine

0.219***

 < 0.001

282

 Sodium

 − 0.221***

 < 0.001

282

 Thyroid-related data

   

 T3

 − 0.356***

 < 0.001

254

 FT3

 − 0.270***

 < 0.001

254

Scores

   

 CTP

0.183**

0.002

282

 MELD

0.425***

 < 0.001

282

 SOFA

0.356***

 < 0.001

282

  1. HBcAb antibody against HBV core; PCT procalcitonin; CRP C-reactive protein; MIP1beta macrophage inflammatory protein 1-beta; INR international normalized ratio; MAP mean arterial pressure; hsTnI hypersensitive troponin I; GFR glomerular filtration rate; T3 Total triiodothyronine; FT3 free triiodothyronine; CTP Child—Turcotte-Pugh; SOFA sequential organ failure assessment, MELD Model for End-stage Liver Disease; UGIB upper gastrointestinal bleeding; WBC white blood cell count. *p < 0.05, **p < 0.01, ***p < 0.001