Fig. 4From: Soluble urokinase plasminogen activator receptor is associated with short-term mortality and enhanced reactive oxygen species production in acute-on-chronic liver failuresuPAR enhanced ROS production in neutrophils in HBV-related ACLF under E.coli stimulation. Whole blood from eight patients with HBV-related ACLF was stimulated with E. coli in the presence of suPAR (50 ng/ml) or PBS for 30 min in vitro. Gating Strategies for ROS detection of neutrophils was shown in (a). The impact of suPAR on neutrophil ROS production was determined in (b). Statistical analyses were performed using the Wilcoxon signed-rank test. *p < 0.05; **p < 0.01Back to article page