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Table 1 Characteristics of including studies

From: The physiological and psychological effects of cognitive behavior therapy on patients with inflammatory bowel disease before COVID-19: a systematic review

References Region Design Duration Participants (age, sex) Sample size Interventions (types, duration) Control
McCombie et al. [51] New Zealand RCT October 29, 2012, until October 2, 2013 Aged 18–65 years; average age: 38.86; male: 71; female: 128; Total (n = 199)
CD(n = 137) UC (n = 54) IBD-U (n = 8)
8-weeks self-administered CCBT: involved 8 sessions with 62 resources TAU
Mikocka-Walus et al. [46] Australia RCT 21/10/2009 and 14/04/2016 Aged 18 years or over; male: 94; female: 80 Total (n = 174)
CD (n = 107) UC (n = 67)
10-weeks CBT (in F2F and CBT group): met weekly at a tertiary hospital for 2 h sessions SC
Mikocka-Walus et al. [45] Australia RCT 21/10/2009 and 14/04/2016 Aged 18 years or over; male: 94; female: 80 Total (n = 174)
CD (n = 107) UC (n = 67)
10-weeks CBT (in F2F and CBT group): met weekly at a tertiary hospital for 2 h sessions sessions; 10 W SC
Wynne et al. [49] Ireland RCT March 2015 and January 2017 Aged between 18 and 65 years; male: 36; female: 43 Total (n = 79)
CD (n = 38) UC (n = 41)
8-weeks ACT: consisted of 8 90-min weekly sessions; Each group consisted of 14–16 particles  
Szigethy et al. [44] America RCT September 2002 and August 2007 Aged between 11 and 17 years; male: 20; female: 21 Total (n = 41)
CD (n = 29) UC (n = 12)
12-weeks PASCET-PI: consisted of nine modules delivered over 9–11 sixty-minute sessions TAU
Berrill et al. [50] England RCT January 2011 and May 2013 Aged 18–65 years; average age:44.9; male: 15; female: 51 Total (n = 66)
CD (n = 21) UC (n = 45)
16-weeks multi-convergent therapy course plus standard medical therapy (MCT) Standard medical therapy
Stapersma et al. [9, 48] Netherlands RCT September 2014 and October 1, 2016 Aged 10–25 years; male: 22; female: 48 Total (n = 70)
(CD:36; UC: 26; IBD-U:8)
12-weeks PASCET-PI; 10 weekly individual sessions CAU
Stapersma et al. [47] Netherlands RCT September 2014 and October 1, 2016 Aged 10–25 years; male: 22; female: 48 Total (n = 70)
CD (n = 36)
UC (n = 26)
IBD-U (n = 8)
12-weeks PASCET-PI; 10 weekly individual sessions CAU
Hunt et al. [42] America RCT   average age(M(SD)):35.64 (13.18); male: 48; female: 92 Total (n = 140)
CD (n = 67)
UC (n = 47)
IBD-U (n = 24)
8-weeks self-help CBT: consisted of a self-help book based on skills and principles used in CBT Psychoeducational workbook
Levy et al. [43] America RCT September 2007 and March 2014 Aged 8 to 17 years; average age:13.5(SD = 2.7); male: 18; female: 167 Total (n = 185)
CD (n = 127)
UC (n = 58)
18.6-days social learning and cognitive behavioural therapy condition (SLCBT) ES
Thompson et al. [41] America RCT   Aged 11–17; male: 20; female: 21 Total (n = 41)
CD (n = 29)
UC (n = 12)
PASCET-PI treatment arm participated in 9–11 individual CBT sessions(supplemented by three parent sessions) TAU
  1. TAU treatment as usual, SC standard care alone, CAU care-as-usual, ES educational support condition, MCT multiconvergent therapy, MBSR mindfulness-based stress reduction, PASCET-PI primary and secondary control enhancement therapy-physical illness