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Table 1 Characteristics of included studies

From: Clinicopathological significance of HSP70 expression in gastric cancer: a systematic review and meta-analysis

Study Country Sample number (PE/NE) Histology (intestinal/diffuse/mixed) Detecting method Cut-off value Positive site Investigating fields Estimates Follow-up (maximum) NOS score
CP features Prognosis
Bodoor et al. [20] Jordan 87(18/69) 49/38/– IHC 20% staining Cytoplasm,Nucleus OR,HR 88 months 7
Chid et al. [28] China 50(39/11) IHC 5% staining Cytoplasm,Nucleus   OR 6
Ando et al. [21] Japan 182(137/45) IHC 70% staining Cytoplasm OR,HR NR 7
Lee et al. [22] Korea 172(50/122) 89/83/– IHC 10% staining Cytoplasm,Nucleus OR,HR NR 8
Kang et al. [23] Korea 458(155/303) 239/219/– IHC 50% staining Cytoplasm OR,HR 83.8 months 8
Pfister et al. [24] Germany 19(7/12) Flow Cytometry 10% staining NR OR,HR 50.4 months 6
Isomoto et al. [25] Japan 81(55/26) IHC 10% staining Cytoplasm,Nucleus OR,HR NR 8
Canöz et al. [26] Turkey 94(87/7) 56/21/17 IHC 5% staining Cytoplasm   OR 7
Maehara et al. [27] Japan 164(82/82) IHC 19% staining Cytoplasm,Nucleus OR,HR NR 8
  1. PE positive expression; NE negative expression; CP clinicopathological; IHC immunohistochemistry; OR odds ratio; HR hazard ratio; NR not reported