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Table 8 The Hex docking analysis between NS5A and NS5B proteins and the approved HCV inhibitors

From: First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients

Proteins

HCV inhibitors

Daclatasvir

Elbasvir

Ledipasvir

Ombitasvir

Dasabuvir

Sofosbuvir

NS5A 1a

 − 313

 − 318

 − 352

 − 330

  

NS5A 1a

(Mutant GLU181)

_

 − 150

_

_

  

NS5A 3a

 − 222

 − 194

 − 222

 − 204

  

NS5B 1a

    

 − 254

 − 282

NS5B 3a

    

 − 224

 − 234