Table 5 Direct oral anticoagulant cessation period
≤ 1-day cessation | > 1-day cessation | p value | |
|---|---|---|---|
n = 17 | n = 25 | ||
EST bleeding | 5 (29.0%) | 1 (4.0%) | 0.032 |
Age > 80 years | 15 (88.0%) | 14 (56.2%) | 0.041 |
Underlying disease‡ | |||
Hemodialysis | 0 | 0 | 1 |
Cardiovascular disease | 4 (24.0%) | 9 (36.0%) | 0.505 |
Stroke | 4 (24.0%) | 9 (36.0%) | 0.505 |
Liver cirrhosis | 3 (18.0%) | 0 | 0.059 |
Combination of antiplatelet drugs | 6 (35.0%) | 6 (24.0%) | 0.498 |
Heparin replacement | 0 | 12 (48.0%) | < 0.001 |
APTT before EST in patients with heparin replacement | 39.6 (31.0–62.6) | ||
Platelet count < 100,000/µl | 2 (12.0%) | 1 (4.0%) | 0.556 |
eGFR | 66.5 (31.3–101.5) | 57.9 (16.4–94.2) | 0.187 |
The number of patients with eGFR < 60 | 5 (29.0%) | 15 (60.0%) | 0.066 |
Patients with eGFR < 60 who were receiving a reduced dose of DOAC | 3/5 (60.0%) | 13/15 (86.7%) | 0.249 |
ERCP findings | |||
Periampullary diverticulum | 4 (24.0%) | 9 (36.0%) | 0.505 |
Precut | 0 | 1 (4.0%) | 0.99 |
Lithotripsy | 14 (82.0%) | 18 (72.0%) | 0.49 |
EPLBD | 1 (6.0%) | 4 (16.0%) | 0.632 |
ENBD | 2 (12.0%) | 1 (4.0%) | 0.556 |
Thromboembolism | 0 | 0 | 1 |