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Table 1 Clinical and biological characteristics of subjects of five groups

From: The liver steatosis severity and lipid characteristics in primary biliary cholangitis

 

PBC (n = 108)

Normal (n = 92)

CHC (n = 92)

CHB (n = 94)

NAFLD (n = 93)

P value

Male gender

8 (7.4%)

8 (8.7%)

8 (8.7%)

8 (8.5%)

7 (7.5%)

0.995

Age (years)

52 (27–69)

52 (26–68)

52 (27–70)

51 (28–68)

52 (27–69)

0.989

BMI (kg/m2)

24.0 (18.0–30.0)

24.0 (17.0–30.0)

24.0 (19.0–30.0)

25.0 (18.0–30.0)

26.0 (18.0–30.0)

0.041

CAP (dB/m)

205.5 ± 34.7

221.1 ± 34.6

243.0 ± 35.7

228.0 ± 32.6

290.4 ± 39.1

< 0.001****

ALT (IU/L)

36.1 (8.0–920.0)

17.5 (3.0–40.0)

20.5 (5.0–1134.0)

23.5 (6.0–929.0)

52.0 (9.0–739.0)

< 0.001****

AST (IU/L)

46.5 (16.0–845.0)

20.0 (10.0–34.0)

24.5 (11.0–514.0)

23.0 (10.0–464.0)

52.0 (15.0–268.0)

< 0.001****

TBil (IU/L)

17.4 (6.7–443.0)

12.5 (6.4–21.0)

15.1 (6.8–109.5)

14.7 (5.9–146.0)

12.9 (6.4–193.5)

< 0.001****

DBil (IU/L)

5.1 (0.8–193.0)

4.2 (1.9–8.4)

5.1 (1.8–47.8)

4.4 (0.6–112.9)

4.0 (1.0–134.3)

0.002***

ALP (IU/L)

142.0 (26.0–1100.0)

71.5 (30.0–189.0)

76.5 (40.0–196.0)

70.0 (37.0–201.0)

87.0 (41.0–206.0)

< 0.001****

GGT (IU/L)

120.0 (9.0–1429.0)

17.0 (8.0–68.0)

20.0 (8.0–286.0)

19.5 (8.0–517.0)

52.5 (10.0–835.0)

< 0.001****

TBA (IU/L)

15.3 (1.3–408.8)

2.6 (0.6–28.7)

3.9 (0.8–73.9)

4.7 (0.8–182.3)

5.4 (1.0–71.3)

< 0.001****

TC (IU/L)

5.0 (1.0–14.0)

4.5 (2.9–5.2)

4.3 (1.0–7.0)

4.6 (2.5–7.7)

5.1 (2.0–7.0)

< 0.001****

TG (IU/L)

1.2 (0.5–7.4)

1.1 (0.5–1.7)

1.0 (0.4–4.4)

1.0 (0.4–6.8)

1.9 (0.6–15.1)

< 0.001****

HDL-C (IU/L)

1.5 (0.2–6.2)

1.3 (0.7–2.7)

1.3 (0.5–2.9)

1.4 (0.2–6.1)

1.2 (0.3–5.7)

< 0.001****

LDL-C (IU/L)

2.6 (0.8–6.2)

2.7 (1.0–3.9)

2.6 (0.6–5.3)

2.8 (1.1–5.9)

3.2 (0.8–5.5)

< 0.001****

  1. Data are shown as mean ± SD (range) or median (range)
  2. BMI, body mass index; CAP, controlled attenuation parameter; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBil, total bilirubin; DBil, direct bilirubin; ALP, alkaline phosphatase; GGT, gamma-glutamyl transferase; TBA, total bile acid; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoproteincholesterol; LDL-C, Low-density lipoprotein cholesterol; PBC, primary biliary cholangitis; CHB, chronic hepatitis B; CHC, chronic hepatitis C; NAFLD, nonalcoholic fatty liver diseas e
  3. *P < 0.05; **P < 0.01; ***P < 0.005; ****P < 0.001