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Table 1 Clinical and biological characteristics of subjects of five groups

From: The liver steatosis severity and lipid characteristics in primary biliary cholangitis

  PBC (n = 108) Normal (n = 92) CHC (n = 92) CHB (n = 94) NAFLD (n = 93) P value
Male gender 8 (7.4%) 8 (8.7%) 8 (8.7%) 8 (8.5%) 7 (7.5%) 0.995
Age (years) 52 (27–69) 52 (26–68) 52 (27–70) 51 (28–68) 52 (27–69) 0.989
BMI (kg/m2) 24.0 (18.0–30.0) 24.0 (17.0–30.0) 24.0 (19.0–30.0) 25.0 (18.0–30.0) 26.0 (18.0–30.0) 0.041
CAP (dB/m) 205.5 ± 34.7 221.1 ± 34.6 243.0 ± 35.7 228.0 ± 32.6 290.4 ± 39.1 < 0.001****
ALT (IU/L) 36.1 (8.0–920.0) 17.5 (3.0–40.0) 20.5 (5.0–1134.0) 23.5 (6.0–929.0) 52.0 (9.0–739.0) < 0.001****
AST (IU/L) 46.5 (16.0–845.0) 20.0 (10.0–34.0) 24.5 (11.0–514.0) 23.0 (10.0–464.0) 52.0 (15.0–268.0) < 0.001****
TBil (IU/L) 17.4 (6.7–443.0) 12.5 (6.4–21.0) 15.1 (6.8–109.5) 14.7 (5.9–146.0) 12.9 (6.4–193.5) < 0.001****
DBil (IU/L) 5.1 (0.8–193.0) 4.2 (1.9–8.4) 5.1 (1.8–47.8) 4.4 (0.6–112.9) 4.0 (1.0–134.3) 0.002***
ALP (IU/L) 142.0 (26.0–1100.0) 71.5 (30.0–189.0) 76.5 (40.0–196.0) 70.0 (37.0–201.0) 87.0 (41.0–206.0) < 0.001****
GGT (IU/L) 120.0 (9.0–1429.0) 17.0 (8.0–68.0) 20.0 (8.0–286.0) 19.5 (8.0–517.0) 52.5 (10.0–835.0) < 0.001****
TBA (IU/L) 15.3 (1.3–408.8) 2.6 (0.6–28.7) 3.9 (0.8–73.9) 4.7 (0.8–182.3) 5.4 (1.0–71.3) < 0.001****
TC (IU/L) 5.0 (1.0–14.0) 4.5 (2.9–5.2) 4.3 (1.0–7.0) 4.6 (2.5–7.7) 5.1 (2.0–7.0) < 0.001****
TG (IU/L) 1.2 (0.5–7.4) 1.1 (0.5–1.7) 1.0 (0.4–4.4) 1.0 (0.4–6.8) 1.9 (0.6–15.1) < 0.001****
HDL-C (IU/L) 1.5 (0.2–6.2) 1.3 (0.7–2.7) 1.3 (0.5–2.9) 1.4 (0.2–6.1) 1.2 (0.3–5.7) < 0.001****
LDL-C (IU/L) 2.6 (0.8–6.2) 2.7 (1.0–3.9) 2.6 (0.6–5.3) 2.8 (1.1–5.9) 3.2 (0.8–5.5) < 0.001****
  1. Data are shown as mean ± SD (range) or median (range)
  2. BMI, body mass index; CAP, controlled attenuation parameter; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBil, total bilirubin; DBil, direct bilirubin; ALP, alkaline phosphatase; GGT, gamma-glutamyl transferase; TBA, total bile acid; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoproteincholesterol; LDL-C, Low-density lipoprotein cholesterol; PBC, primary biliary cholangitis; CHB, chronic hepatitis B; CHC, chronic hepatitis C; NAFLD, nonalcoholic fatty liver diseas e
  3. *P < 0.05; **P < 0.01; ***P < 0.005; ****P < 0.001