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Table 1 Characteristics of the patients

From: Regorafenib combined with transarterial chemoembolization for unresectable hepatocellular carcinoma: a real-world study

Characteristic

Total (n = 38)

Age (years)

59.4 ± 9.2

Median (range)

60 (35, 79)

Sex, n (%)

Male

32 (84.2)

Female

6 (15.8)

ECOG performance status, n (%)

0

20 (52.6)

1

13 (34.2)

2

5 (13.2)

BCLC grade, n (%)

B

18 (47.4)

C

20 (52.6)

Hepatitis, n (%)

Hepatitis B

32 (84.2)

Hepatitis C

2 (5.3)

No

4 (10.5)

Maximum tumor size (cm)

3.75 (0.9, 15.1)

Tumor number, n (%)

Single

4 (10.5)

Multiple

32 (84.2)

Unknown

2 (5.3)

Child–Pugh grade, n (%)

A

37 (97.4)

B

1 (2.6)

Macrovascular invasion, n (%)

12 (31.6)

AFP ≥ 400 μg/L, n (%)

11 (28.9)

Comorbidity, n (%)

Hypertension

15 (39.5)

Diabetes Mellitus

4 (10.5)

Extrahepatic metastasis, n (%)

13 (34.2)

Prior local therapy, n (%)

Surgery

13 (34.2)

Ablation

20 (52.6)

TACE

36 (94.7)

Radiotherapy

6 (15.8)

Prior systemic therapy, n (%)

Sorafenib

33 (86.8)

Lenvatinib

1 (2.6)

Lenvatinib sequential to sorafenib

4 (10.5)

Follow-up (months), median (range)

5.6 (0.7, 17.0)

  1. ECOG Eastern Cooperative Oncology Group, BCLC Barcelona clinic liver cancer, AFP α-fetoprotein, TACE transarterial chemoembolization