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Table 3 Performance of logistic regression model of CRC at different sensitivity thresholds for CRC detection

From: Multivariable models for advanced colorectal neoplasms in screen-eligible individuals at low-to-moderate risk of colorectal cancer: towards improving colonoscopy prioritization

Performance characteristic Sensitivity of CRC detection
100% 99% 95%
% missed CRC 0 0.58 5.2
% missed HRA 31.5 35.7 68.2
% colonoscopies avoided 44.1 50.0 79.1
  1. Interpretation (100% Column): At the minimum probability cut point to permit 100% CRC detection, the model predicts a miss rate of 0% for CRC and 31.5% for HRA and reduces colonoscopy burden by 44.1%