Multivariable models for advanced colorectal neoplasms in screen-eligible individuals at low-to-moderate risk of colorectal cancer: towards improving colonoscopy prioritization

Table 3 Performance of logistic regression model of CRC at different sensitivity thresholds for CRC detection

Performance characteristic	Sensitivity of CRC detection
Performance characteristic	100%	99%	95%
% missed CRC	0	0.58	5.2
% missed HRA	31.5	35.7	68.2
% colonoscopies avoided	44.1	50.0	79.1

Interpretation (100% Column): At the minimum probability cut point to permit 100% CRC detection, the model predicts a miss rate of 0% for CRC and 31.5% for HRA and reduces colonoscopy burden by 44.1%

ISSN: 1471-230X