Skip to main content

Table 2 Clinical characteristics of the training cohort related to fibrosis stage

From: Cytokeratin 18 can help predict liver fibrosis in HCV infected patients with type 2 diabetes mellitus

Variables Spearman correlation analysis Multivariable analysis
r2 value P value b coefficient P value
Age (years) 0.018 .124 NA NA
Sex (male, female) 0.023 .085 NA NA
BMI 0.001 .743 NA NA
Child–Pugh (A, B + C) 0.003 .142 NA NA
ALT (U/L) 0.001 .761 NA NA
AST (U/L) 0.021 .146 NA NA
ALP (U/L) 0.018 .124 NA NA
GGT (U/L) 0.024 .076 NA NA
TB (µmol/L) 0.019 .117 NA NA
CB (µmol/L) 0.031 .102 NA NA
ALB (g/L) 0.085 .001 − 0.030 .008
GLOB (g/L) 0.013 .064 NA NA
CRP (mg/L) 0.009 .088 NA NA
WBC (109/L) 0.038 .024 NA .916
PLT (109/L) 0.189 < .001 NA .279
PT (s) 0.092 < .001 NA .304
INR 0.121 < .001 NA .198
Cholesterol (mmol/L) 0.000 .914 NA NA
TG (mmol/L) 0.026 .065 NA NA
HDL-C 0.005 .402 NA NA
LDL-C 0.002 .688 NA NA
FBG (mmol/L) 0.016 .153 NA NA
FINS (mIU/L) 0.015 .048 NA .234
IR 0.012 .026 NA .131
TE (kPa) 0.736 < .001 0.189 < .001
CK18 (ng/L) 0.211 < .001 0.009 < .001
  1. b coefficients are from multivariable linear regression
  2. ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CK18, cytokeratin 18; CRP, C reactive protein; FBG, fasting blood glucose; FINS, fasting insulin; GGT, γ-glutamyl transferase; GLOB, globulin; HDL-C, high density lipoprotein cholesterol; INR, international normalized ratio; IR, insulin resistance; LDL-C, low density lipoprotein cholesterol; TE, transient elastography; TG, triglyceride; PLT, blood platelet; PT, prothrombin time; TB, serum total bilirubin; WBC, white blood cell