Table 2 Clinical characteristics of the training cohort related to fibrosis stage
Variables | Spearman correlation analysis | Multivariable analysis | ||
|---|---|---|---|---|
r2 value | P value | b coefficient | P value | |
Age (years) | 0.018 | .124 | NA | NA |
Sex (male, female) | 0.023 | .085 | NA | NA |
BMI | 0.001 | .743 | NA | NA |
Child–Pugh (A, B + C) | 0.003 | .142 | NA | NA |
ALT (U/L) | 0.001 | .761 | NA | NA |
AST (U/L) | 0.021 | .146 | NA | NA |
ALP (U/L) | 0.018 | .124 | NA | NA |
GGT (U/L) | 0.024 | .076 | NA | NA |
TB (µmol/L) | 0.019 | .117 | NA | NA |
CB (µmol/L) | 0.031 | .102 | NA | NA |
ALB (g/L) | 0.085 | .001 | − 0.030 | .008 |
GLOB (g/L) | 0.013 | .064 | NA | NA |
CRP (mg/L) | 0.009 | .088 | NA | NA |
WBC (109/L) | 0.038 | .024 | NA | .916 |
PLT (109/L) | 0.189 | < .001 | NA | .279 |
PT (s) | 0.092 | < .001 | NA | .304 |
INR | 0.121 | < .001 | NA | .198 |
Cholesterol (mmol/L) | 0.000 | .914 | NA | NA |
TG (mmol/L) | 0.026 | .065 | NA | NA |
HDL-C | 0.005 | .402 | NA | NA |
LDL-C | 0.002 | .688 | NA | NA |
FBG (mmol/L) | 0.016 | .153 | NA | NA |
FINS (mIU/L) | 0.015 | .048 | NA | .234 |
IR | 0.012 | .026 | NA | .131 |
TE (kPa) | 0.736 | < .001 | 0.189 | < .001 |
CK18 (ng/L) | 0.211 | < .001 | 0.009 | < .001 |