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Table 1 Main characteristics

From: Cytokeratin 18 can help predict liver fibrosis in HCV infected patients with type 2 diabetes mellitus

Parameter

Training (n = 132)

Validation (n = 120)

P value

Sex

  

.614

 No. of men

72 (54.5)

61 (50.8)

 

 No. of women

60 (45.5)

59 (49.2)

 

Age

  

.703

 < 60 (years)

76 (57.6)

72 (60.0)

 

 ≥ 60 (years)

56 (42.4)

48 (40.0)

 

BMI

23.86 ± 3.06

23.67 ± 2.88

.618

Laboratory findingsa

   

 WBC (109/L)

5.45 ± 2.15

5.20 ± 2.04

.354

 FBG (mmol/L)

8.6 ± 4.2

9.3 ± 5.4

.250

 FINS (mIU/L)

14.86 ± 10.37

16.33 ± 11.49

.287

 AST (IU/mL)

57.59 ± 68.80

69.88 ± 121.65

.319

 ALT (IU/mL)

86.45 ± 145.88

87.22 ± 169.00

.969

 GGT (IU/mL)

92.16 ± 118.81

77.40 ± 106.36

.302

 ALP (IU/mL)

98.39 ± 60.50

87.78 ± 67.94

.191

 Platelet count (109/L)

151.96 ± 59.70

148.97 ± 68.49

.711

 Cholesterol (mmol/L)

3.96 ± 1.00

4.04 ± 0.92

.527

 TG (mmol/L)

1.80 ± 1.21

1.60 ± 1.05

.106

 INR

1.17 ± 0.18

1.17 ± 0.15

.774

 APRI

1.17 ± 1.58

1.52 ± 3.31

.275

 FIB-4

2.16 ± 1.67

2.69 ± 3.42

.117

Histologic activity grade

  

.271

 A0

27 (20.5)

23 (19.2)

.875

 A1

49 (37.1)

57 (47.5)

.099

 A2

40 (30.3)

32 (26.7)

.577

 A3

16 (12.1)

8 (6.7)

.197

Histologic fibrosis stage

  

.787

 F0

11 (8.3)

10 (8.3)

> .99

 F1

16 (12.1)

21 (17.5)

.285

 F2

25 (18.9)

21 (17.5)

.871

 F3

29 (22.0)

22 (18.3)

.531

 F4

51 (38.6)

46 (38.3)

.961

TE (kPa)

11.13 ± 5.21

11.05 ± 5.87

.914

CK18 (ng/L)

105.41 ± 28.33

103.24 ± 26.67

.533

  1. Except where indicated, data are numbers of patients, with percentages in parentheses
  2. ALT, alanine transferase; ALP, alkaline phosphatase; APRI, aspartate transaminase-to-platelet ratio; AST, aspartate transaminase; BMI, body mass index; CK18, cytokeratin 18; FBG, fasting blood glucose; FINS, fasting insulin; FIB-4, fibrosis-4 index; GGT, γ-glutamyl transferase; INR, international normalized ratio; TE, transient elastography; TG, triglyceride; WBC, white blood cell
  3. aData are presented as means ± standard deviations