Cyclin-dependent kinase 19 upregulation correlates with an unfavorable prognosis in hepatocellular carcinoma

BMC Gastroenterology

Table 1 Correlations between CDK19 and immune cells’ gene markers in HCC

Cells subtypes	Markers	Non-purity adjusted		Purity adjusted
Cells subtypes	Markers	ρ(rho)	P	ρ(rho)	P
B cells	CD19	0.213	4.90E−04	0.245	8.60E−05
	CD79A	0.189	2.60E−03	0.26	1.90E−05
T cells (general)	CD3D	0.173	4.70E−03	0.237	1.80E−04
	CD2	0.183	2.30E−03	0.272	5.80E−06
	CD3E	0.182	2.10E−03	0.278	3.20E−06
CD8 + T cells	CD8B	0.126	5.00E−02	0.186	2.60E−03
	CD8A	0.195	1.20E−03	0.265	7.70E−06
CD4 + T cells	QRSL1	0.698	2.60E−54	0.7	5.10E−51
	STAT1	0.443	4.20E−18	0.469	5.30E−19
	STAT4	0.312	1.60E−08	0.348	3.70E−10
	STAT5A	0.404	7.60E−15	0.435	3.10E−16
	STAT6	0.339	1.10E−10	0.335	1.00E−09
	CD4	0.303	1.70E−08	0.362	5.20E−11
	TBX21	0.096	1.60E−01	0.16	9.40E−03
Tumur associated macrophages	CCL2	0.217	2.10E−04	0.289	4.50E−07
	CD68	0.193	1.30E−03	0.239	6.90E−05
	IL10	0.264	1.00E−05	0.34	1.80E−09
Type I macrophages	IRF5	0.483	1.90E−21	0.483	6.40E−20
	NOS2	0.156	6.10E−03	0.172	3.30E−03
	PTGS2	0.364	8.50E−12	0.467	1.60E−18
Type II macrophages	CD163	0.15	1.00E−02	0.216	1.70E−04
	MS4A4A	0.156	8.60E−03	0.235	5.40E−05
	VSIG4	0.173	3.40E−03	0.245	2.90E−05
Neutrophil	CCR7	0.181	2.30E−03	0.26	9.90E−06
	ITGAM	0.315	5.20E−09	0.365	2.60E−11
Dendritic cells	CD1C	0.252	6.00E−06	0.3	1.30E−07
	HLA-DPB1	0.175	3.70E−03	0.234	7.30E−05
	HLA-DQB1	0.086	2.80E−01	0.133	4.80E−02
	HLA-DRA	0.171	4.60E−03	0.23	7.90E−05
	ITGAX	0.337	1.00E−09	0.425	6.20E−15
	NRP1	0.459	1.00E−19	0.469	2.70E−19

ISSN: 1471-230X