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Table 2 Factors associated with the risk of intestinal resection

From: Perianal disease onset age is associated with distinct disease features and need for intestinal resection in perianal Crohn’s disease: a ten-year hospital-based observational study in China

Factors

Univariate analysis

Multivariate analysis

OR (95% CI)

P-value

OR (95% CI)

P value

All PCD patients (n = 293)

    

Male

1.727 (0.883–3.379)

0.110

0.488 (0.194–1.225)

0.126

AOP

2.887 (1.511–5.515)

0.001

4.939 (1.538–15.855)

0.007

Behaviour

 

0.019

 

0.070

 B2 versus B1

2.097 (1.194–3.685)

0.010

1.810 (1.008–3.251)

0.047

 B3 versus B1

2.329 (0.833–6.513)

0.107

2.291 (0.789–6.651)

0.127

IFX + PSIs

0.270 (0.063–1.163)

0.079

0.243 (0.049–1.206)

0.083

Rectal inflammation

2.462 (1.050–5.769)

0.038

3.166 (1.119–8.959)

0.030

Patients with AOP (n = 209)

    

PCD diagnostic delay

0.944 (0.986–1.001)

0.109

0.994 (0.986–1.001)

0.109

Behaviour

 

0.061

 

0.089

 B1 versus B3

3.488 (0.435–27.976)

0.239

3.595 (0.440–29.390)

0.233

 B2 versus B3

6.769 (0.858–53.416)

0.070

6.563 (0.817–52.714)

0.077

IFX + PSIs

0.324 (0.073–1.433)

0.138

0.374 (0.082–1.712)

0.205

Complex perianal fistulas

2.297 (1.089–4.848)

0.029

2.257 (1.041–4.891)

0.039

Patients with POP (n = 84)

    

Family history of IBD

4.102 (0.861–19.532)

0.076

2.670 (0.273–26.148)

0.399

Rectal inflammation

9.000 (2.099–17.210)

0.009

7.000 (1.876–15.407)

0.012

  1. *CD Crohn’s disease, PD perianal disease, B1 non-stricturing and non-penetrating, B2 stricturing, B3 penetrating, IFX infliximab, PSIs perianal surgical interventions, PCD perianal Crohn’s disease, AOP adult-onset perianal disease, POP paediatric-onset perianal disease, IBD inflammatory bowel disease
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BMC Gastroenterology

ISSN: 1471-230X

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