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Table 4 Effect of combination of age and Gender on the predictive capability of malignancy in patients with uncomplicated dyspepsia (n = 4037)

From: Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings

 

Age

Gender

Gender for malignancy

F

F

M

M

< 50

> 50

Female

Male

< 57

> 57

< 56

> 56

Total n. patients

2553

1484

2397

1640

1857

540

1266

374

Malignancy (n, 45)

4

41

12

33

1

11

5

28

OR

1.12

4.40

1.12

1.12

[95% CI]

[1.09, 1.15]

[2.24, 8.62]

[1.06, 1.18]

[1.08, 1.16]

AUC

0.775

0.665

0.841

0.871

[95% CI]

[0.721, 0.829]

[0.651, 0.680]

[0.826, 0.856]

[0.854, 0.887]

Sensitivity

91.11%

73.33%

91.67%

84.85%

[95% CI]

[78.8, 97.5]

[58.1, 85.4]

[61.5, 99.8]

[68.1, 94.9]

Specificity

65.53%

59.74%

77.82%

78.47%

[95% CI]

[64.0, 67.0]

[58.2, 61.3]

[76.1, 79.5]

[76.4—80.5]

LR+

2.64

1.82

4.13

3.94

[95% CI]

[2.4, 2.9]

[1.5, 2.2]

[3.4, 5.0]

[3.3—4.7]

LR-

0.14

0.45

0.11

0.19

[95% CI]

[0.05, 0.3]

[0.3, 0.7]

[0.02, 0.7]

0.09—0.4

  1. OR odd ratios, AUC area under curve, 95% CI confidence interval, LR likelihood