Table 1 Comparison of clinical and pathological characteristics between patients with pre-operative ALBI grades I and II

Age (years; mean ± SD)

65.2 ± 12.2

58.9 ± 11.8

64.8 ± 12

Male, n (%)

131 (78%)

56 (84.8%)

75 (73.5%)

Diabetes mellitus, n (%)

58 (34.5%)

22 (33.3%)

36 (35.3%)

Hypertension, n (%)

90 (58.1%)

37 (60.7%)

53 (56.4%)

Etiology

 Alcohol^$, n (%)

32 (19.0%)

16 (24.2%)

16 (15.7%)

 NAFLD, n (%)

49 (29.2%)

24 (36.4%)

25 (24.5%)

 AIH, n (%)

14 (8.3%)

3 (4.5%)

11 (10.8%)

 Unclassified, n (%)

73 (43.5%)

23 (34.8%)

50 (49.0%)

Current alcohol intake^$, n (%)

32 (24.2%)

16 (32.7%)

16 (19.3%)

AST (U/L; mean ± SD)

41.6 ± 74.4

34.7 ± 19.3

46.1 ± 94.1

ALT (U/L; mean ± SD)

44.1 ± 109.4

39.5 ± 23.3

47.2 ± 139.3

Total bilirubin (mg/dL; mean ± SD)

0.8 ± 0.3

0.8 ± 0.3

0.8 ± 0.4

Albumin (g/dL; mean ± SD)

3.7 ± 0.6

4.2 ± 0.3

3.4 ± 0.4

Platelet (< 150,000 u/L), n (%)

38 (22.9%)

14 (21.5%)

24 (23.8%)

AFP (> 200 ng/mL), n (%)

25 (15.3%)

11 (16.9%)

14 (14.3%)

Liver cirrhosis, n (%)

38 (22.6%)

13 (19.7%)

25 (24.5%)

Tumor size (cm; mean ± SD)

5.3 ± 3.7

4.5 ± 2.9

5.9 ± 4.1

Tumor number (single:multiple)

164:4

65:1

99:3

Child–Pugh grade (A:B)

158:10

66:0

92:10

BCLC stage (0:A:B)

17:87:64

10:35:21

7:52:43

Pathological features

Fat content (%) in nontumor tissue, n (%)**

 > 30%

24 (17.5%)

15 (26.3%)

9 (11.3%)

 5–30%

37 (27.0%)

15 (26.3%)

22 (27.5%)

 < 5%

76 (55.5%)

27 (47.4%)

49 (61.3%)

Microvascular invasion, n (%)

55 (35%)

19 (29.7%)

36 (38.7%)

pTNM stage (I:II:III)

101:58:8

41:23:1

60:3 5:7

Histological grade (well:moderate:poor)

31:125:11

14:50:2

17:75:9