Fig. 4
From: Sodium nitroprusside protects HFD induced gut dysfunction via activating AMPKα/SIRT1 signaling
SNP resisted HFD inhibited colonic AMPKα/SIRT1 signaling. Mice (n = 6) were fed with ND or HFD for 16 weeks. SNP was supplemented in drinking water (1 mg/mL) from the fifth week of feeding to the end of the experiment. A NO levels of colon; B–D Protein levels of phosphorylated AMPKα and SIRT1 (n = 4); E Correlation between colonic NO content and phosphorylated AMPKα; F Correlation between colonic NO content and SIRT1. Data were presented as the mean ± S.E.M. (* p < 0.05, **p < 0.01, ***p < 0.001)