Fig. 3
From: Sodium nitroprusside protects HFD induced gut dysfunction via activating AMPKα/SIRT1 signaling
SNP ameliorated HFD-induced intestinal barrier dysfunction. Mice (n = 6) were fed with ND or HFD for 16 weeks. SNP was supplemented in drinking water (1 mg/mL) from the fifth week of feeding to the end of the experiment. A Representative pictures of colons of each group; B Colon length; C Serum FITC-dextran levels; D IL-6 levels of colon; E-G Protein levels of intestinal barrier indicators ZO-1 and occludin (n = 4); (H) Representative histological pictures of hematoxylin and eosin staining. Data were presented as the mean ± S.E.M. (*p < 0.05, **p < 0.01, ***p < 0.001)