Table 5 Comparison of responders and non-responders to steroid therapy

14 steroid-resistant

18 steroid-dependent

Age, mean ± SD (years)

46.1 ± 17.8

43.5 ± 19.8

0.606

Sex, M/F

15 (62.5%)/9 (37.5%)

16 (50.0%)/16 (50.0%)

0.421

BMI, mean ± SD (kg/m²)

23.3 ± 4.6

23.0 ± 3.9

0.83

History of smoking

9 (37.5%)

11 (34.4%)

1

Current alcohol consumption

6 (25.0%)

8 (25.0%)

1

Age at onset, mean ± SD (years)

38.9 ± 17.7

37.8 ± 19.9

0.82

Disease duration, median (range), years

6.0 (0–9)

3.5 (1–9.5)

0.71

Type

1

Extensive

20 (83.3%)

27 (84.4%)

Left-sided

4 (16.7%)

5 (15.6%)

Proctitis

0 (0%)

0 (0%)

Frequency of defecation per day, median (range)

5 (3–8)

8 (5–12)

0.017

Bloody stool

11 (45.8%)

27 (84.4%)

0.004

CRP, median (range), mg/dL

0.29 (0.05–2.1)

1.18 (0.35–6.0)

0.074

Alb, median (range), g/dL

4.1 (3.6–4.4)

3.4 (2.7–4.1)

0.006

Plt, median (range), × 10⁴/μL

29.9 (21.8–37.8)

39.0 (28.3–45.6)

0.066

Fecal hemoglobin, median (range), ng/mL

999 (50–5664)

3630 (1329–9417)

0.074

CMV infection

2 (8.3%)

3 (9.4%)

1

MES, median (range)

3 (2–3)

3 (3–3)

0.081

Matts grade, median (range)

4 (3–5)

5 (4–5)

0.015

Partial Mayo score

6 (5–7)

7 (5–9)

0.45

PR3-ANCA positive

10 (41.7%)

23 (71.9%)

0.030

PR3-ANCA, median (range), U/mL

1.9 (1.2–7.5)

8.9 (1.9–25.5)

0.041