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Table 4 Diagnostic performance of each type in the NICE clasification stratified by polyp size

From: Utility of the narrow-band imaging international colorectal endoscopic classification for optical diagnosis of colorectal polyp histology in clinical practice: a retrospective study

Type of classification

Sensitivity (%) (95% CI)

Specificity (%) (95% CI)

PPV (%) (95% CI)

NPV (%) (95% CI)

Accuracy (%) (95% CI)

Type 1

     

 < 10 mm

81.2 (63.6–92.8)

99.4 (97.9–99.9)

92.9 (76.5–99.1)

98.2 (96.2–99.3)

97.8 (95.8–99.1)

 ≥ 10 mm

100.0 (61.5–100.0)

100.0 (96.5–100.0)

100.0 (61.5–100.0)

100.0 (96.5–100.0)

100.0 (96.7–100.0)

 All size

86.0 (72.1–94.7)

99.6 (98.5–100.0)

94.9 (82.7–99.4)

98.8 (97.4–99.6)

98.5 (97.1–99.4)

Type 2

     

 < 10 mm

99.1 (97.4–99.8)

82.4 (65.5–93.2)

98.2 (96.2–99.3)

90.3 (74.2–98.0)

97.6 (95.4–98.9)

 ≥ 10 mm

99.3 (96.2–100.0)

90.0 (68.3–98.8)

98.6 (95.2–99.8)

94.7 (74.0–99.9)

98.2 (94.8–99.6)

 All size

99.2 (97.9–99.8)

85.2 (72.9–93.4)

98.3 (96.8–99.3)

92.0 (80.8–97.8)

97.8 (96.1–98.8)

Type 3

     

 < 10 mm

100.0 (9.4–100.0)

99.7 (98.5–100.0)

66.7 (9.4–99.2)

100.0 (98.5–100.0)

99.7 (98.5–100.0)

 ≥ 10 mm

77.8 (40.0–97.2)

99.4 (96.5–100.0)

87.5 (47.3–99.7)

98.7 (95.5–99.8)

98.2 (94.8–99.6)

 All size

81.8 (48.2–97.7)

99.6 (98.6–100.0)

81.8 (48.2–97.7)

99.6 (98.6–100.0)

99.3 (98.1–99.8)

Determination of neoplastic polyp (Type 2/3)

     

 < 10 mm

99.4 (97.9–99.9)

81.2 (63.6–92.8)

98.2 (96.2–99.3)

92.9 (76.5–99.1)

97.8 (95.8–99.1)

 ≥ 10 mm

100.0 (96.5–100.0)

100.0 (61.5–100.0)

100.0 96.5–100.0)

100.0 (61.5–100.0)

100.0 (96.7–100.0)

 All size

99.6 (98.5–100.0)

86.0 (72.1–94.7)

98.8 (97.4–99.6)

94.9 (82.7–99.4)

98.5 (97.1–99.4)

  1. The sensitivity, specificity, PPV, NPV, and accuracy of each type do not differ significantly between polyp sized < 10 mm and ≥ 10 mm
  2. NICE classification narrow-band imaging international colorectal endoscopic classification, CI confidence interval, PPV positive predictive value, NPV negative predictive value