Prognostic nutritional index is an independent prognostic factor for older patients aged ≥ 85 years treated by gastric endoscopic submucosal dissection

Table 3 Overall survival by the Kaplan–Meier method

Variable	No. of patients	OS	P value
Gender
Male	42	0.50	0.19
Female	28	0.57
ECOG PS
0–1	61	0.57	0.11
2–3	9	0.22
GNRI
≥ 92	60	0.55	0.35
< 92	10	0.40
CCI
0–2	59	0.54	0.22
≥ 3	11	0.46
NLR
≥ 2.6	30	0.43	0.066
< 2.6	40	0.60
PNI
≥ 42.5	60	0.58	0.001
< 42.5	10	0.20
Serum albumin
≥ 3.5 g/dl	60	0.58	0.029
< 3.5 g/dl	10	0.20
Tumor location
Upper	13	0.62	0.98
Middle	23	0.48
Lower	34	0.53
Tumor size
≥ 20 mm	17	0.53	0.66
< 20 mm	53	0.53
Macroscopic appearance
Elevated	40	0.45	0.11
Depressed/flat	30	0.63
Histology
Differentiated type	69	0.52	0.60
Undifferentiated type	1	1.00
Depth of invasion
M/SM1	67	0.51	0.63
SM2	3	1.00
Lymphatic invasion
Present	4	0.50	0.88
Absent	66	0.53
Ulcerative findings
Present	7	0.43	0.80
Absent	63	0.54
Curability
eCuraA/B	62	0.53	0.76
eCuraC-2	8	0.50

OS, overall survival; ECOG PS, Eastern Cooperative Oncology Group performance status; GNRI, geriatric nutritional risk index; CCI, Charlson comorbidity index; NLR, Neutrophil to lymphocyte ratio; PNI, Prognostic nutritional index; M, mucosa; SM1, superficial portion of the submucosa within 500 μm from the muscularis mucosae; SM2, deep portion of the submucosa ≥ 500 μm from the muscularis mucosae

ISSN: 1471-230X